Improved methodology for the asymmetric alkylation of aldehydes employing bis(sulfonamide) complexes

DOI: 10.1016/S0040-4039(98)01220-9

Source and publish data:

Tetrahedron Letters p. 5941 - 5942 (1998)

Update date:2022-08-17

Topics:

Authors:

Pritchett, Suzy

Woodmansee, David H.

Davis, Timothy J.

Walsh, Patrick J.

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Article abstract of DOI:10.1016/S0040-4039(98)01220-9

We report an improved procedure for the asymmetric transfer of alkyl groups from zinc to aldehydes utilizing bis(sulfonamide) ligands. The new methodology is easier to perform and, in some cases, provides the alcohol products with higher enantioselectivit

Full text of DOI:10.1016/S0040-4039(98)01220-9

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