Synthesis and structure-activity relationships of a novel antifungal agent, azoxybacilin

DOI: 10.1248/cpb.42.1703

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1703 - 1705 (1994)

Update date:2022-08-16

Topics:

Authors:

Ohwada Ohwada

Umeda Umeda

Ontsuka Ontsuka

Aoki Aoki

Shimma Shimma

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.1703

A new antifungal substance, azoxybacilin (an unusual amino acid with an azoxy moiety) and its derivatives have been synthesized from Boc-L-Asp-O(t)Bu utilizing the Moss procedure for the preparation of the azoxy moiety. The ester derivative, Ro 09-1824, showed more potent antifungal activity and a broader antifungal spectrum than azoxybacilin did.

Full text of DOI:10.1248/cpb.42.1703

NII-Electronic Library Service

Products guided by the article

Product name:(S)-N-Boc-γ-Iodo-Abu-OtBu

Cas No:161370-66-7

R&D Labs maybe for 161370-66-7

HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou
Shanghai Surseechem Co.,Ltd.

Contact:+86-21-61318535

Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
SYN Pharma Co., Ltd

Contact:86-21 60347964

Address:No.1304, West Meilong Road, Minhang District, Shanghai, China
Chemsky（shanghai）International Co.,Ltd.

Contact:0

Address:0
Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,

Relevant to this article

Doi:10.1021/ja01855a048
()
Controllable Pt nanoparticle deposition on carbon nanotubes as an anode catalyst for direct methanol fuel cells

Doi:10.1021/jp0555448
(2005)
Reaction of the closo-decaborate anion B₁₀H ₁₀ ^2- with dichloroethane in the presence of hydrogen halides

Doi:10.1134/S0036023607070042
(2007)
Green Microwave-assisted Multicomponent Route to the Formation of 5,8-Dihydropyrido[2,3-d]pyrimidine Skeleton in Aqueous Media

Doi:10.1002/jhet.2586
(2017)
A CaMnAl-hydrotalcite solid basic catalyst toward the aldol condensation reaction with a comparable level to liquid alkali catalysts

Doi:10.1039/c8gc00851e
(2018)
N-Ethylpiperidine Hypophosphite Mediated Intermolecular Radical Carbon-Carbon Bond Forming Reaction in Water

Doi:10.1055/s-2002-33508
(2002)

Article Doi