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Total Synthesis of (+/-)-Calanolide A, a Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase

DOI: 10.1021/jo00073a015

Source and publish data:

Journal of Organic Chemistry p. 5605 - 5606 (1993)

Update date:2022-08-10

Topics:

Authors:

Chenera, BalanChenera, Balan

West, Michael L.West, Michael L.

Finkelstein, Joseph A.Finkelstein, Joseph A.

Dreyer, Geoffrey B.Dreyer, Geoffrey B.

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Article abstract of DOI:10.1021/jo00073a015

The first syntheses of (+/-)-calanolide A and the related (+/-)-calanolides C and D have been carried out in a short sequence using a Lewis acid-promoted Claisen rearrangement to establish the chromene ring.

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Full text of DOI:10.1021/jo00073a015

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