A Useful Oxidation Procedure for the Preparation of 3-Alkanoyltetronic Acids

DOI: 10.1055/s-1997-960

Source and publish data:

Synlett p. 909 - 910 (1997)

Update date:2022-08-17

Topics:

Authors:

Mittra, Asmita

Yamashita, Masayuki

Kawasaki, Ikuo

Murai, Hiromichi

Yoshioka, Tomomichi

Ohta, Shunsaku

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Article abstract of DOI:10.1055/s-1997-960

An easy and convenient synthesis of 3-alkanoyl-5-hydroxymethyltetronic acids, the salts of which have inhibitory activity against HIV-1 protease, is described and a new direct route to 1,3-dicarbonylester from cyclic β-ketoester is developed.

Full text of DOI:10.1055/s-1997-960

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