Tetrahedron Letters p. 2663 - 2666 (1998)
Update date:2022-08-11
Topics:
Kearney, Patrick C.
Fernandez, Monica
Flygare, John A.
A method for the solid-phase synthesis of disubstituted guanidines is reported. In this procedure, polymer-bound aryl or alkyl amines are converted to methyl isothioureas in three steps and treated with primary and secondary amines to form the disubstitut
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