Lanthanide triflate-catalyzed 1,3-dipolar cycloaddition reactions of polymer-supported nitrones with alkenes for the preparation of diverse 2- isoxazoline derivatives

Article abstract of DOI:10.1016/S0040-4039(98)02100-5

1,3-Dipolar cycloaddition reactions of polymer-supported nitrones with alkenes proceeded smoothly in the presence of a catalytic amount of a lanthanide triflate to afford the corresponding 2-isoxazolines in high yields. Diverse 2-isoxazoline derivatives were prepared based on these solid- phase reactions.