Probing the importance of spacial and conformational domains in captopril analogs for angiotensin converting enzyme activity

Article abstract of DOI:10.1016/S0960-894X(98)00377-1

A new synthesis of 4,5-methano-L-prolines and the enzymatic activity of the corresponding N-(3-mercapto-2-R-methyl-propionyl) analogs as inhibitors of angiotensin converting enzyme are described.