Tetrahedron Asymmetry p. 3309 - 3314 (1996)
Update date:2022-08-29
Topics:
Antolini, Luciano
Forni, Arrigo
Moretti, Irene
Prati, Fabio
Laurent, Eliane
Gestmann, Detlef
Ethyl trans-3-(trifluoromethyl)pyroglutamate 1 is synthesized in excellent yield; racemic 1 is enzymatically resolved with α-chymotrypsin-catalyzed hydrolysis affording both the enantiomerically pure enantiomers. The absolute configuration is established
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