Tetrahedron Letters p. 7629 - 7632 (1997)
Update date:2022-08-11
Topics:
De Kort, Martin
Valentijn, A. Rob P.M.
Van Der Marel, Gijs A.
Van Boom, Jacques H.
Three new potential ligands for the IP3 receptor (i.e. compounds 5-7) were prepared by Sonogashira coupling of propargyl 2-O-acetyl-5-O-benzyl-3-O-(3,4-di-O-acetyl-2,6-di-O-benzyl-α-D-glucopyranosyl) -β-D-ribofuranoside (15) with iodobenzene, 1,2-diiodobenzene and 1,2,4,5-tetraiodobenzene, followed by deacetylation, phosphorylation and deprotection.
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