Bioorganic and Medicinal Chemistry Letters p. 1013 - 1018 (1999)
Update date:2022-08-16
Topics:
Lee, Koo
Hwang, Sang Yeul
Park, Cheol Won
A series of novel arylsulfonylpropargylglycinamide derivatives was investigated as thrombin inhibitors in which the SAR was focused on substituents at the acetylchic terminus. Several compounds in this series were identified as potent thrombin inhibitors (Ki up to 5 nM) that are highly selective over trypsin and other serine proteases as well.
View More
Contact:86-571-87758773
Address:Room604 ,6F, Block A1-3 Xixi Plaza,No. 588 Wenyi West RD, Hangzhou,310012, China
taicang liyuan chemical co,.ltd
website:http://www.tcliyuanchem.com/productse.php
Contact:86-512-53539583
Address:Room 804,Huaxu Building,No.95,Renmin South Road,Taicang city,Jiangsu Province,China
ZhangJiaGang YaRui Chemical Co.,Ltd.
Contact:0512-58360968
Address:China JiangSu Province Zhang Jia Gang City YangShe Oriental Plaza Building 10 B307
AstaTech ( Chengdu) BioPharmaceutical Corp.
website:http://www.astabiochem.cn/
Contact:+86-15198215156-15198215156
Address:SICHUAN CHENGDU
Wuhan Better Organic Technology Inc.
Contact:13307163183
Address:Wuhan Economic&Technology Development Zone, Hubei
Doi:10.1071/CH9761815
(1976)Doi:10.1016/j.phytochem.2006.11.012
(2007)Doi:10.1039/f19848000617
(1984)Doi:10.1016/j.ica.2012.11.010
(2013)Doi:10.1021/ic50007a067
(1963)Doi:10.1021/ja01620a060
(1955)
