Phytochemistry p. 1585 - 1588 (1982)
Update date:2022-08-24
Topics:
Pfitzner, Artur
Stoeckigt, Joachim
The characterization and partial purification of geissoschizine dehydrogenase from Catharanthus roseus cell suspension cultures are described.The 35-fold purified enzyme removes the 21α-hydrogen of geissoschizine in a NADP+-dependent reaction.NAD+, FAD or FMN cannot act as cofactors for the dehydrogenation.Structurally related indole alkaloids are not dehydrogenated.In comparison to enzymes of the ajmalicine pathway, geissoschizine dehydrogenase shows an extremely low specific activity. - Key Word Index: Catharanthus roseus; Apocynaceae; geissoschizine dehydrogenase; stereospecificity; biosynthesis; heteroyohimbine alkaloids; cell suspension culture.
View More
Contact:86-575-86132822，86-575-86085355
Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.
Suzhou Credit International Trading Co., Ltd
Contact:+86-512-65398039
Address:Qingdeng, Hightech. District, Suzhou
Luzhou North Chemical Co., Ltd.
Contact:+86-830-2796784；+86-830-2796776
Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
Nantong Baokai Chemical Co., Ltd (Hangzhou Baokai Bio-Chemicals Co.,Ltd.)
Contact:+86-513-83886111
Address:No. 68 Suzhou road ,Binjiang Fine Chemical Industrial Park , Beixin town, Qidong city ,Jiangsu province
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Contact:+86-21-5161 3915
Address:Shanghai YangPu
Doi:10.1016/j.jorganchem.2011.02.016
(2011)Doi:10.1021/jo0511400
(2005)Doi:10.1016/j.tetlet.2006.10.038
(2006)Doi:10.1016/0022-328X(90)85219-O
(1990)Doi:10.1002/1521-3773(20011001)40:19<3596::AID-ANIE3596>3.0.CO;2-C
(2001)Doi:10.1055/s-0040-1708004
(2020)
