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Synthesis of pyranoquinoline alkaloids via (4+2) cycloaddition reaction

DOI: 10.1515/HC.2005.11.1.79

Source and publish data:

Heterocyclic Communications p. 79 - 84 (2005)

Update date:2022-08-16

Topics:

Authors:

SureshSuresh

DhanabalDhanabal

Nandha KumarNandha Kumar

MohanMohan

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Article abstract of DOI:10.1515/HC.2005.11.1.79

An easy route to synthesize pyranoquinoline based alkaloids like flindersine, haplamine, N-methylflindersine and its derivatives were performed from the respective 4-hydroxyquinolin-2(1H)-one, dimethyl acrylic acid and para formaldehyde through generation of O-quinone methide intermediates and subjecting (4+2) cycloaddition. Further, dihydro intermediates were oxidized by DDQ.

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Full text of DOI:10.1515/HC.2005.11.1.79

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Brought to you by | University of Arizona  
Authenticated  
Download Date | 5/30/15 2:54 PM  
Brought to you by | University of Arizona  
Authenticated  
Download Date | 5/30/15 2:54 PM  
Brought to you by | University of Arizona  
Authenticated  
Download Date | 5/30/15 2:54 PM  
Brought to you by | University of Arizona  
Authenticated  
Download Date | 5/30/15 2:54 PM  
Brought to you by | University of Arizona  
Authenticated  
Download Date | 5/30/15 2:54 PM  

Products guided by the article

Product name:7-methoxy-2,2-dimethyl-2,3,4,6-tetrahydro-5H-pyrano[3,2-c]quinolin-5-one

Cas No:3921-69-5

3921-69-5

R&D Labs maybe for 3921-69-5

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