Alkylglycidic Acids: Potential New Hypoglycemic Agents

DOI: 10.1021/jm00161a009

Source and publish data:

Journal of Medicinal Chemistry p. 2184 - 2190 (1986)

Update date:2022-08-25

Topics:

Authors:

Ho, Winston

Tutwiler, Gene F.

Cottrell, Sandra C.

Morgans, Dave J.

Tarhan, Okan

Mohrbacher, Richard J.

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Article abstract of DOI:10.1021/jm00161a009

A series of alkylglycidic acid analogues and derivatives were synthesized and tested for their ability to inhibit long-chain fatty acid oxidation in vitro and to lower blood sugar in rats.The extent of inhibition of carnitine acyl transferase, the enzyme

Full text of DOI:10.1021/jm00161a009

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