Synthesis of cystamidin A (pyrrole-3-propanamide), a reported calpain inhibitor

DOI: 10.1016/S0960-894X(96)00269-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1541 - 1542 (1996)

Update date:2022-08-11

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Authors:

Bihovsky, Ron

Pendrak, Israil

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Article abstract of DOI:10.1016/S0960-894X(96)00269-7

The reported calpain inhibitor cystamidin A (1a, pyrrole-3-propanamide) and a regioisomer, pyrrole-2-propanamide (1b) have been synthesized from the corresponding pyrrolecarboxaldehydes. The previously assigned structure of cystamidin A is confirmed. However, neither synthetic cystamidin A nor regioisomer 1b inhibits recombinant human calpain I.

Full text of DOI:10.1016/S0960-894X(96)00269-7

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Product name:METHYL 3-(2-PYRROLYL)PROPANOATE

Cas No:69917-80-2

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SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.

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