Debenzylation of complex oligosaccharides using ferric chloride

Article abstract of DOI:10.1016/0040-4039(96)01169-0

Anhydrous FeCl₃ in CH₂Cl₂ at room temperature and 0°C has been used to debenzylate monosaccharides and oligosaccharides in yields generally greater than 70%. Notably, alkenes, acetates, benzoates, phthalimides, acyl amides, and sensitive glycosidic linkages are unaffected by the reaction conditions.