Publication and Further Research

Synthesis Characterization Optimization Data Analysis Structure-Activity Relationship (SAR) Analysis Purification and characterization Materials and Reagents Chemical Synthesis In vitro Testing Biological Assays Structure-Activity Relationship (SAR) Studies In Vivo Testing Literature Review Biological Evaluation Safety and Toxicity Assessment In Vivo Studies Lead Optimization Design Toxicity Studies Pharmacokinetics Data Analysis and Reporting Synthesis of Pyrazole-4-Carboxamide Derivatives Selection of Staphylococcus aureus Strains Assessment of Biofilm Formation Treatment with Pyrazole-4-Carboxamide Derivatives Measurement of Biofilm Inhibition Analysis of Biofilm Inhibition Mechanisms Relevance to Clinical Applications Design and Synthesis Pharmacokinetic Studies In Vitro Antimycobacterial Evaluation Cytotoxicity Assessment Perform computational studies to support the experimental findings. This could involve Antifungal Activity Evaluation Synthesis of Nicotinamide Derivatives Testing and Validation Toxicity and Pharmacokinetics Radiolabeling (if applicable) Fluorescent Tagging (if applicable) Mechanism of Action Studies Cellular Distribution Studies Antioxidant Activity Evaluation Antibacterial Activity Evaluation Cell Studies Bioavailability Studies Choice of Quinazolinone Derivative Synthesis and Modification Sensing Mechanism Selectivity Enhancement Fluorophore Attachment