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5-METHYL-3-PHENYL-1,2,4-OXADIAZOLE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1198-98-7

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1198-98-7 Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 125, 1989 DOI: 10.1002/jhet.5570260122The Journal of Organic Chemistry, 50, p. 1182, 1985 DOI: 10.1021/jo00208a008

Check Digit Verification of cas no

The CAS Registry Mumber 1198-98-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1198-98:
(6*1)+(5*1)+(4*9)+(3*8)+(2*9)+(1*8)=97
97 % 10 = 7
So 1198-98-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O/c1-7-10-9(11-12-7)8-5-3-2-4-6-8/h2-6H,1H3

1198-98-7 Well-known Company Product Price

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  • Alfa Aesar

  • (B20145)  5-Methyl-3-phenyl-1,2,4-oxadiazole, 97%   

  • 1198-98-7

  • 1g

  • 546.0CNY

  • Detail
  • Alfa Aesar

  • (B20145)  5-Methyl-3-phenyl-1,2,4-oxadiazole, 97%   

  • 1198-98-7

  • 5g

  • 2185.0CNY

  • Detail

1198-98-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-METHYL-3-PHENYL-1,2,4-OXADIAZOLE

1.2 Other means of identification

Product number -
Other names 3-phenyl-5-methyl-1,2,4-oxadiazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1198-98-7 SDS

1198-98-7Relevant academic research and scientific papers

The reaction of amidoximes with carboxylic acids or their esters under high-pressure conditions

Baikov,Stashina,Chernoburova,Krylov,Zavarzin,Kofanov

, p. 347 - 350 (2019)

3,5-Disubstituted 1,2,4-oxadiazoles were synthesized by the reaction of amidoximes with carboxylic acids or their esters under high-pressure conditions (10 kbar). The reaction proceeds without the use of other reagents or catalysts. Both aliphatic and aro

SYNTHESIS AND SPECTROSCOPIC STUDIES OF 5-METHYL-3-PHENYL- AND 5-METHYL-3-(o-, m-, AND p-TOLYL)-1,2,4-OXADIAZOLES.

Srivastava,Mendes e Silva

, p. 221 - 223 (1984)

Preparation of four 1,2,4-oxadiazoles, 2a-d, from O-acetyl derivatives of benzamidoximes, 1a-d, are reported. Two of them, viz. , 2b,c, were not encountered in the literature. Spectroscopic studies (IR, UV, and **1H NMR) were carried out to learn more abo

Reaction of amidoximes with acetonitrile at high pressure

Baykov, Sergey V.,Zharov, Aleksey A.,Stashina, Galina A.,Zavarzin, Igor V.,Kofanov, Evgeniy R.

, p. 264 - 265 (2016)

Reaction of amidoximes with acetonitrile giving 1,2,4-oxadiazoles occurs at 80-100 °C under a pressure of 10 Kbar without catalysts.

Convenient one-pot synthesis of 1,2,4-oxadiazoles and 2,4,6-triarylpyridines using graphene oxide (GO) as a metal-free catalyst: Importance of dual catalytic activity

Basak, Puja,Dey, Sourav,Ghosh, Pranab

, p. 32106 - 32118 (2021/12/02)

A convenient and efficient process for the synthesis of 3,5-disubstituted 1,2,4-oxadiazoles and 2,4,6-triarylpyridines has been described using an inexpensive, environmentally benign, metal-free heterogeneous carbocatalyst, graphene oxide (GO). GO plays a dual role of an oxidizing agent and solid acid catalyst for synthesizing 1,2,4-oxadiazoles and triarylpyridines. This dual catalytic activity of GO is due to the presence of oxygenated functional groups which are distributed on the nanosheets of graphene oxide. A broad scope of substrate applicability and good sustainability is offered in this developed protocol. The results of a few control experiments reveal a plausible mechanism and the role of GO as a catalyst was confirmed by FTIR, XRD, SEM, and HR-TEM analysis.

2-Iodosylbenzoic acid activated by trifluoromethanesulfonic anhydride: Efficient oxidant and electrophilic reagent for preparation of iodonium salts

Huss, Christopher D.,Kitamura, Tsugio,Saito, Akio,Yoshimura, Akira,Zhdankin, Viktor V.

supporting information, p. 16434 - 16437 (2021/10/01)

2-Iodosylbenzoic acid in the presence of trifluoromethanesulfonic anhydride is an efficient oxidant and electrophilic reagent useful for preparation of the corresponding alkenyl and aryliodonium salts. Compared to the previously reported methods of electr

Imidazole hydrochloride promoted synthesis of 3,5-disubstituted-1,2,4-oxadiazoles

Wang, Xuetong,Wang, Yin,Liu, Xiaoling,He, Tingshu,Li, Lingli,Wu, Huili,Zhou, Shangjun,Li, Dan,Liao, Siwei,Xu, Ping,Huang, Xing,Yuan, Jianyong

, (2021/10/14)

Imidazole hydrochloride as an additive promotes the reaction of amidoximes and DMA derivatives to generated 3,5-disubstituted-1,2,4-oxadiazoles in low to excellent yields without the use of coupling reagents, oxidants, strong acids or bases and other additives.

Efficient insecticidal aerosol and preparation method thereof

-

, (2020/10/30)

The invention provides an efficient insecticidal aerosol, which comprises the following components in percentage by weight: 0.1-0.5wt% of a component A, i.e. a 1, 2, 4-diazole derivative shown as a formula I, 1-1.5wt% of a component B, i.e. a marigold ext

Potassium Poly(Heptazine Imide): Transition Metal-Free Solid-State Triplet Sensitizer in Cascade Energy Transfer and [3+2]-cycloadditions

Antonietti, Markus,Guldi, Dirk M.,Hussain, Tanveer,Karton, Amir,Markushyna, Yevheniia,Mazzanti, Stefano,Oschatz, Martin,Sánchez Vadillo, José Manuel,Savateev, Aleksandr,Strauss, Volker,Tarakina, Nadezda V.,Tyutyunnik, Alexander P.,Walczak, Ralf,ten Brummelhuis, Katharina

, p. 15061 - 15068 (2020/06/17)

Polymeric carbon nitride materials have been used in numerous light-to-energy conversion applications ranging from photocatalysis to optoelectronics. For a new application and modelling, we first refined the crystal structure of potassium poly(heptazine imide) (K-PHI)—a benchmark carbon nitride material in photocatalysis—by means of X-ray powder diffraction and transmission electron microscopy. Using the crystal structure of K-PHI, periodic DFT calculations were performed to calculate the density-of-states (DOS) and localize intra band states (IBS). IBS were found to be responsible for the enhanced K-PHI absorption in the near IR region, to serve as electron traps, and to be useful in energy transfer reactions. Once excited with visible light, carbon nitrides, in addition to the direct recombination, can also undergo singlet–triplet intersystem crossing. We utilized the K-PHI centered triplet excited states to trigger a cascade of energy transfer reactions and, in turn, to sensitize, for example, singlet oxygen (1O2) as a starting point to synthesis up to 25 different N-rich heterocycles.

Efficient Synthesis of Functionalized Indene Derivatives via Rh(III)-Catalyzed Cascade Reaction between Oxadiazoles and Allylic Alcohols

Zhang, Jing,Sun, Jun-Shu,Xia, Ying-Qi,Dong, Lin

supporting information, p. 2037 - 2041 (2019/03/28)

A highly efficient rhodium(III)-catalyzed synthesis of novel functionalized indene derivatives has been achieved via C?H activation/intramolecular aldol condensation. This cascade reaction is an atom economical protocol which could be further applied to build more complex compounds. (Figure presented.).

Rhodium-catalyzed synthesis of 1-(acylamino)isoquinolines through direct annulative coupling of 3-aryl-1,2,4-oxadiazoles with alkynes

Nishii, Yuji,Bachon, Anne-Katrin,Moon, Sanghun,Bolm, Carsten,Miura, Masahiro

supporting information, p. 1347 - 1349 (2017/08/14)

A Rh(III)-catalyzed direct annulative coupling of 3-aryl-1,2,4-oxadiazoles with alkynes through coordination-assisted CH activation is developed, providing a facile route to 1-(acylamino)isoquinolines. The oxadiazole ring acts as a directing group as well as an internal oxidant.

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