135-57-9Relevant articles and documents
Preparation method of high-quality peptizer
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Paragraph 0020-0027, (2021/01/28)
The invention discloses a preparation method of a high-quality peptizer DBD, which belongs to the technical field of chemical engineering. The method comprises the following steps: after benzothiazoleis subjected to a ring-opening reaction, adding a certain volume of an organic solvent for dissolution, then carrying out an oxidation reaction, and finally carrying out an acylation reaction to prepare the peptizer DBD. In the process provided by the invention, the production efficiency and quality of an intermediate diphenyl amino disulfide are improved, the oxidation reaction and acylation reaction are facilitated, and the yield and quality of the final peptizer DBD are improved; solid-liquid separation and other treatment on the intermediate diphenyl amino disulfide are not needed, the technological process is simple, and wastewater discharge is reduced; according to the method, the organic solvent is recycled, the COD content in the produced wastewater is low, the post-treatment wastewater cost is easy to reduce, and the whole method is high in environmental friendliness.
Copper-Catalyzed Arylation of Benzothiazoles with Toluene Derivatives: Synthesis of 2-Arylbenzothiazole
Li, Chengliang,Deng, Hongmei,Jin, Tao,Liu, Zhiqiang,Jiang, Ruolan,Li, Chunju,Jia, Xueshun,Li, Jian
, p. 4350 - 4356 (2017/09/12)
A copper-catalyzed reaction of benzothiazole and readily available toluene derivatives has been disclosed. This protocol is proposed to proceed through the oxidation of toluene and ring opening of benzothiazole, thus providing a new pathway for the synthesis of 2-arylbenzothiazoles..
Aerobic Copper-Mediated Domino Three-Component Approach to 2-Aminobenzothiazole Derivatives
Castanheiro, Thomas,Suffert, Jean,Gulea, Mihaela,Donnard, Morgan
, p. 2588 - 2591 (2016/06/15)
An unprecedented three-component reaction involving a 2,2′-diaminodiaryl disulfide, copper cyanide, and an electrophile is described. This transformation is based on an oxidative copper-mediated S-cyanation as a key step and involves a cyanation/cyclization/acylation domino sequence enabling a rapid and efficient synthesis of diversely substituted 2-aminobenzothiazole derivatives. Notably, this reaction proceeds via an original mechanism involving an intermolecular migration of the acyl group.