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Stilben-4-ol is a phenol compound characterized by a stilbene structure with a hydroxy function at the C-4 position of one of the phenyl rings. It exhibits a diverse range of biological activities and potential applications across various industries.

3839-46-1

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3839-46-1 Usage

Uses

Used in Pharmaceutical Industry:
Stilben-4-ol is used as a pharmaceutical agent for its potential therapeutic effects. It has been found to possess antioxidant, anti-inflammatory, and anticancer properties, making it a promising candidate for the development of new drugs to treat various diseases.
Used in Cosmetic Industry:
In the cosmetic industry, stilben-4-ol is used as an active ingredient in skincare products due to its antioxidant and anti-aging properties. It helps protect the skin from environmental stressors and promotes collagen production, resulting in improved skin elasticity and reduced appearance of fine lines and wrinkles.
Used in Food and Beverage Industry:
Stilben-4-ol is used as a natural preservative and antioxidant in the food and beverage industry. It helps extend the shelf life of products by preventing oxidation and spoilage, while also providing potential health benefits to consumers.
Used in Agricultural Industry:
Stilben-4-ol can be used in the agricultural industry as a natural pesticide or growth promoter. Its bioactive properties may help protect crops from pests and diseases, while also promoting healthy growth and development.
Overall, stilben-4-ol is a versatile compound with a wide range of applications across various industries, from pharmaceuticals and cosmetics to food and agriculture. Its unique structure and biological activities make it a valuable asset for the development of new products and treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 3839-46-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,3 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3839-46:
(6*3)+(5*8)+(4*3)+(3*9)+(2*4)+(1*6)=111
111 % 10 = 1
So 3839-46-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H12O/c15-14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-11,15H/b7-6+

3839-46-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name stilben-4-ol

1.2 Other means of identification

Product number -
Other names Stilbene-4-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3839-46-1 SDS

3839-46-1Relevant academic research and scientific papers

Aminomethylpyridinequinones as new ligands for PEPPSI-type complexes

Gajda, Roman,Poater, Albert,Brotons-Rufes, Artur,Planer, Sebastian,Wo?niak, Krzysztof,Grela, Karol,Kajetanowicz, Anna

, p. 138 - 156 (2021/03/22)

A set of six new catalysts possessing quinone moieties in a pyridine ligand was synthesized and fully characterized by standard analytical techniques, including X-Ray crystallography. The results obtained in Suzuki and Mizoroki–Heck cross-coupling reactions catalyzed by quinone-based compounds were comparable to these obtained in the presence of the original PEPPSI complex designed by Organ. DFT calculations allow to see the structural and electronic factors to describe their similarity. On the other hand, steric maps and NCI plots were the tools to have a more global view of the systems studied, leaving the sphere of reactivity around the metal.

Palladium supported aminobenzamide modified silica coated superparamagnetic iron oxide as an applicable nanocatalyst for Heck cross-coupling reaction

Fatahi, Yousef,Ghaempanah, Aram,Ma?mani, Leila,Mahdavi, Mohammad,Bahadorikhalili, Saeed

, (2021/01/26)

An applicable palladium-based nanocatalyst was constructed through the immobilization of palladium onto 2-aminobenzamide functionalized silica coated superparamagnetic iron oxide magnetic nanoparticles. The nanocatalyst (named as Pd@ABA@SPIONs@SiO2) was characterized by several characterization methods, including scanning electron microscope (SEM), transmission electron microscopy (TEM), vibrating-sample magnetometry (VSM), energy-dispersive X-ray spectroscopy (EDS), dynamic light scattering (DLS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), inductively coupled plasma (ICP), and X-ray photoelectron spectroscopy (XPS) analyses. Microscopy results showed that the nanoparticles are spherical in shape with 20–25 nm size. The size of the nanoparticles was confirmed by the DLS method. The superparamagnetic nature of the catalyst was confirmed by the VSM method. The successful functionalization of SPIONs@SiO2 was confirmed by FT-IR spectroscopy. The presence of palladium in the structure of the nanocatalyst was illustrated by XRD and EDS analysis. Also using XPS technique, the oxidation state of palladium in Pd@ABA@SPIONs@SiO2 was determined zero before and after the catalyst was applied in Mizoroki-Heck reaction. Several aryl halides and alkenes were reacted in the presence of the nanocatalyst and formed the corresponding products in high isolated yields. The nanocatalyst showed very good reusability and did not decrease its activity after 10 sequential runs. Density functional theory (DFT) calculation was performed to provide a mechanism for the reaction and confirmed the role of the palladium catalyst in the reaction function.

Cleavage of aryl-ether bonds in lignin model compounds using a Co-Zn-beta catalyst

Chang, Hou-Min,Dou, Xiaomeng,Jameel, Hasan,Jiang, Xiao,Li, Wenzhi,Zhu, Chaofeng

, p. 43599 - 43606 (2020/12/25)

Efficient cleavage of aryl-ether linkages is a key strategy for generating aromatic chemicals and fuels from lignin. Currently, a popular method to depolymerize native/technical lignin employs a combination of Lewis acid and hydrogenation metal. However, a clear mechanistic understanding of the process is lacking. Thus, a more thorough understanding of the mechanism of lignin depolymerization in this system is essential. Herein, we propose a detailed mechanistic study conducted with lignin model compounds (LMC) via a synergistic Co-Zn/Off-Al H-beta catalyst that mirrors the hydrogenolysis process of lignin. The results suggest that the main reaction paths for the phenolic dimers exhibiting α-O-4 and β-O-4 ether linkages are the cleavage of aryl-ether linkages. Particularly, the conversion was readily completed using a Co-Zn/Off-Al H-beta catalyst, but 40% of α-O-4 was converted and β-O-4 did not react in the absence of a catalyst under the same conditions. In addition, it was found that the presence of hydroxyl groups on the side chain, commonly found in native lignin, greatly promotes the cleavage of aryl-ether linkages activated by Zn Lewis acid, which was attributed to the adsorption between Zn and the hydroxyl group. Followed by the cobalt catalyzed hydrogenation reaction, the phenolic dimers are degraded into monomers that maintain aromaticity. This journal is

Stereoselective Rhodium-Catalyzed Isomerization of Stereoisomeric Mixtures of Arylalkenes

Yang, Hongxuan,Dong, Wenke,Wang, Wencan,Li, Tao,Zhao, Wanxiang

supporting information, p. 2833 - 2840 (2020/10/06)

A new efficient method for the synthesis of a high ratio of E -alkenes from E / Z mixtures of alkenes with B 2pin 2in the presence of a rhodium catalyst is described. This reaction features mild reaction conditions, broad functional group tolerance, and highly great application potential.

Synthesis of Pd@graphene oxide framework nanocatalyst with enhanced activity in Heck-Mizoroki cross-coupling reaction

Shekarizadeh, Arezoo,Azadi, Roya

, (2020/05/22)

A new method was developed for producing a catalyst involving a Pd nanoparticle (NP) embedded in a graphene oxide framework (Pd@GOF) with ordered macro- and mesoporous structures. First, 5,5′-diamino-2,2′-bipyridine was selected as cross-linking for covalent modification of GO nanosheets to prepare a three-dimensional (3D) framework with interlayer spaces in which well-dispersed and ultra-small Pd NPs in situ grew and embedded the framework. The synthesized nanopores 3D Pd@GOF can act as nanoreactors to help the reaction substrates thoroughly come into contact with the surface of Pd NPs, thereby exhibiting high activity toward the Heck reaction, rarely reported concerning Pd NPs supported on one-side functionalized graphene. The Pd@GOF catalyst can be used 10 times without any significant loss in the catalytic activity, confirming the long-term stability of this catalyst. Therefore, the covalently assembled GOF was proposed as a universal platform for hosting noble metal NPs to construct the desired metal@GOF nanocatalyst with improved activity and stability that can be used in a broad range of practical applications.

3D-Printed Phenacrylate Decarboxylase Flow Reactors for the Chemoenzymatic Synthesis of 4-Hydroxystilbene

Peng, Martin,Mittmann, Esther,Wenger, Lukas,Hubbuch, Jürgen,Engqvist, Martin K. M.,Niemeyer, Christof M.,Rabe, Kersten S.

supporting information, p. 15998 - 16001 (2019/11/22)

Continuous flow systems for chemical synthesis are becoming a major focus in organic chemistry and there is a growing interest in the integration of biocatalysts due to their high regio- and stereoselectivity. Methods established for 3D bioprinting enable the fast and simple production of agarose-based modules for biocatalytic reactors if thermally stable enzymes are available. We report here on the characterization of four different cofactor-free phenacrylate decarboxylase enzymes suitable for the production of 4-vinylphenol and test their applicability for the encapsulation and direct 3D printing of disk-shaped agarose-based modules that can be used for compartmentalized flow microreactors. Using the most active and stable phenacrylate decarboxylase from Enterobacter spec. in a setup with four parallel reactors and a subsequent palladium(II) acetate-catalysed Heck reaction, 4-hydroxystilbene was synthesized from p-coumaric acid with a total yield of 14.7 % on a milligram scale. We believe that, due to the convenient direct immobilization of any thermostable enzyme and straightforward tuning of the reaction sequence by stacking of modules with different catalytic activities, this simple process will facilitate the establishment and use of cascade reactions and will therefore be of great advantage for many research approaches.

Cobalt catalyzed stereodivergent semi-hydrogenation of alkynes using H2O as the hydrogen source

Li, Kangkui,Khan, Ruhima,Zhang, Xuexin,Gao, Yang,Zhou, Yongyun,Tan, Heng,Chen, Jingchao,Fan, Baomin

, p. 5663 - 5666 (2019/05/21)

Cobalt-catalyzed stereodivergent semi-hydrogenation of internal alkynes to alkenes is developed. The reaction proceeded through transfer hydrogenation under mild conditions using a base metal CoI2 as the catalyst, and H2O/MeOH as the hydrogen source with Zn as the reductant. The E/Z-selectivity of the product could be switched by changing the solvent and by inclusion/exclusion of a bidentate phosphine ligand (dppe). This method provides a simple and cost effective pathway for the synthesis of 1,2-dideuterioalkenes.

Thermo-responsive poly(N -isopropylacrylamide)- block -poly(ionic liquid) of pyridinium sulfonate immobilized Pd nanoparticles in C-C coupling reactions

Ghasemi, Soheila,Harandi, Zahra Amini

, p. 14570 - 14578 (2018/04/26)

A thermo-responsive poly(N-isopropylacrylamide)-block-poly(ionic liquid) (PNIPAM-b-PIL) of pyridinium-type was prepared. Initially, controlled synthesis of PNIPAM was performed via RAFT method. Subsequently, PNIPAM as macromolecular chain transfer agent (macro-CTA) was used for fabrication of PNIPAM-b-PIL through reaction with a synthesized IL monomer i.e. 4-vinyl pyridinium propane sulfonate. The Pd catalyst was produced throughout palladium nanoparticles' anchoring into this block copolymer. The catalyst was characterized using ICP, FT-IR, NMR, UV-Vis, TGA, XRD, SEM and EDX techniques. The catalyst's TEM image proved nearly fine dispersion of PdNPs with negligible agglomeration. The catalyst was used in the production of a variety of substituted alkenes and biaryl compounds (Heck and Suzuki coupling) in organic and aqueous media and under solvent free conditions. Additionally, the results signified extreme reusability of the catalyst with a simple recycling procedure.

Facile synthesis of magnetic recyclable palladium-gold alloy nanoclusters catalysts PdAur/Fe3O4@LDH and its catalytic applications in Heck reaction

Li, Jin,Wang, Yajuan,Jiang, Shunwang,Zhang, Hui

, p. 84 - 95 (2018/10/24)

A series of novel magnetic recyclable Pd–Au nanoclusters (NCs) catalysts x-PdAur/Fe3O4@LDH (x: Pd loading in wt%, r: Au/Pd molar ratio, LDH: layered double hydroxide, here refers the typical MgAl-LDH) were synthesized by a facile polyol reduction followed sol immobilization of PdAur–PVP on core@shell support Fe3O4@LDH. Systematic characterizations reveal that the obtained catalysts possess the honeycomb-like core@shell, and the ultrafine PdAu alloy nanoclusters with the size in 1.70–2.55 nm highly dispersed on the LDH nanoplates shell. The obtained catalysts 1.0-PdAur/Fe3O4@LDH (r: 0.11, 0.16 and 0.48) show higher Heck activity of iodobenzene with styrene than monomentallic ones, especially 1.0-PdAu0.16/Fe3O4@LDH displays the highest Heck activity under the optimal condition. Moreover, the catalysts can be applied for the Heck reaction of a variety of aryl halides with alkenes, and can be conveniently separated by an external magnet and reused ten runs without significant loss of activity.

Enhanced photocatalytic activity of gold nanoparticles driven by supramolecular host-guest chemistry

Padilla, Marc,Peccati, Francesca,Bourdelande, José Luis,Solans-Monfort, Xavier,Guirado, Gonzalo,Sodupe, Mariona,Hernando, Jordi

supporting information, p. 2126 - 2129 (2017/02/19)

Functionalization of gold nanoparticles with supramolecular hosts allows their plasmon-based photocatalytic activity to be enhanced. This is mainly ascribed to the formation of labile host-guest complexes with the reagent molecules on the metal surface, thus promoting nanoparticle-substrate approximation without interfering with the light-induced catalytic process.

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