Cyclopropanation with low catalyst loading

July 17, 2024

• Title:       

  Cyclopropanation with low catalyst loading

• Image Source:

  Palladium-catalyzed synthesis of diarylbenzenes from coupling reactions between equal amount of diiodoarenes and arylboronic acids

• Mark:

  Scheme 1

• Associated context:

  Only 3 equiv of CH₂N₂ (CAS 420-04-2), calculated from the Nmethyl-Nnitroso urea engaged) were required to afford complete conversion of vinyl silane 5 to adduct 1l(reaction on a 4g scale)over 45 min (Scheme 1).