The six-atom distance between the basic nitrogen and ether oxygen

July 26, 2024

• Title:       

  The six-atom distance between the basic nitrogen and ether oxygen

• Image Source:

  Synthesis and structure-activity relationships of long-acting β2 adrenergic receptor agonists incorporating arylsulfonamide groups

• Mark:

  Figure 2

• Associated context:

  The six-atom distance between the basic nitrogen and ether oxygen is present, however, in a diverse number of other β2 agonists including salmeterol (CAS 89365-50-4), formoterol (CAS 128954-45-0), picumeterol (CAS 130641-36-0), salmefamol (CAS 18910-65-1), carmoterol (CAS 147568-66-9), and sibenadet (CAS 154189-40-9) (Figure 2). This observation has been noted and commented upon by other groups.