Synthesis of 1,2-fluoroethylamines by using novel prochiral fluoride synthon

July 26, 2024

• Title:       

  Synthesis of 1,2-fluoroethylamines by using novel prochiral  

  fluoride synthon

• Image Source:

  Chiral monofluorobenzyl carbanions: Synthesis of enantiopure β-fluorinated β-phenylethylamines

• Mark:

  Scheme 1

• Associated context:

  Hence, we decided to evaluate the potential of (S)-2-p-tolylsulfinylbenzyl fluoride (S)-1 as a precursor of stabilized monofluorinated benzyl carbanion (Scheme 1).