NBS and TCCA Treatment of 4,4-Dimethylcyclohexene-Fused Isoxazoline N-Oxide Derivative

August 19, 2024

• Title:       

  NBS and TCCA Treatment of 4,4-Dimethylcyclohexene-Fused Isoxazoline N-Oxide Derivative

• Image Source:

  Halonium ion mediated synthesis of 2-halomethylene-3-oxoketoxime derivatives from isoxazoline N-oxides

• Mark:

  Scheme 2

• Associated context:

  In order to extend the scope of our protocol, we treated 4,4-dimethyl-substituted cyclohexene fused isoxazoline N-oxide derivative with NBS and TCCA (Scheme 2). In both cases, the product was obtained in good yields; however, NBS was found to be more productive than TCCA.