127-09-3

Basic information

• Product Name: Sodium acetate
• Synonyms: SODIUM ACETATE ANHYDROUS CELL CULTUR;Sodium acetate anhydrous for analysis EMSURE ACS,Reag. Ph Eur;SODIUM ACETATE ANHYDROUS, FOR MOLECU;Sodium acetate anhydrous, free-flowing, Redi-Dri, ACS reagent, >=99.0%;SODIUM ACETATE BIOXTRA;SODIUM ACETATE SOLUTION, F. MOL. BIO;SODIUM ACETATE, ANHYDROUS, FOR&;Sodium acetate, anhydrousACS/USP/FCC, 99.0-101.0% (Titration: after drying)
• CAS NO: 127-09-3
• Molecular Formula: C₂H₃O₂*Na
• Molecular Weight: 82.03379
• EINECS: 204-823-8
• Product Categories: Food Additives;INORGANIC & ORGANIC CHEMICALS;Other Buffer SolutionsSynthetic Reagents;Buffer Convenience Packaging;Buffer Solutions;Buffer SolutionsBiological Buffers;Buffers A to ZpH Buffers for Titration;Inorganic Salts;AlphabeticalMolecular Biology;Biological Buffers;BioUltra Buffers;BioUltraBiological Buffers;Buffer SolutionsProtein Structural Analysis;DNA&RNA Purification;Molecular Biology Reagents;Optimization ReagentsMolecular Biology;Reagents;X-Ray Crystallography;Alphabetical Listings;Flavors and Fragrances;Q-Z;metal acetate salt;Auxiliary or oragnic intermediates;Food additive
• Mol File: 127-09-3.mol
• Article Data: 55

Chemical Properties

• Melting Point: >300 °C (dec.)(lit.)
• Boiling Point: 117.1 °C at 760 mmHg
• Flash Point: >250 °C
• Appearance: white/powder
• Density: 1.01 g/mL at 20 °C
• Vapor Pressure: 13.9mmHg at 25°C
• Refractive Index: 1.4640
• Storage Temp.: 2-8°C
• Solubility: H2O: 3 M at 20 °C, clear, colorless
• PKA: 4.756[at 20 ℃]
• Water Solubility: 500 g/L (20 ºC)
• Sensitive: Hygroscopic
• Stability: Stable. Incompatible with strong oxidizing agents, halogens. Moisture sensitive.
• Merck: 14,8571
• BRN: 3595639
• CAS DataBase Reference: Sodium acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium acetate(127-09-3)
• EPA Substance Registry System: Sodium acetate(127-09-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 1
• RTECS: AJ4300010
• F: 3
• TSCA: Yes
• Hazardous Substances Data: 127-09-3(Hazardous Substances Data)

Usage

Chemical Description

Different sources of media describe the Chemical Description of 127-09-3 differently. You can refer to the following data:
1. Sodium acetate is a salt commonly used as a buffer in biochemistry.
2. Sodium acetate is a salt commonly used in the textile industry.
3. Sodium acetate is a white crystalline powder that is used in the textile industry.

Description

Sodium acetate (CH3COONa) is the sodium salt of acetic acid. It appears as a colorless deliquescent salt with a wide range of applications. In industry, it can be used in textile industry to neutralize sulfuric acid waste streams and as a photoresist upon using aniline dyes. In concrete industry, it can be used as a concrete sealant to mitigate the water damage. In food, it can be used as a seasoning. It can also be used as a buffer solution in lab. In addition, it is also used in heating pads, hand warmers and hot ice. For laboratory use, it can be produced by the reaction between acetate with the sodium carbonate, sodium bicarbonate and sodium hydroxide. In industry, it is prepared from the glacial acetic acid and sodium hydroxide.

Chemical Properties

Different sources of media describe the Chemical Properties of 127-09-3 differently. You can refer to the following data:
1. Anhydrous salt is a colorless crystalline solid; density 1.528 g/cm3; melts at 324°C; very soluble in water; moderately soluble in ethanol. The colorless crystalline trihydrate has a density 1.45 g/cm3; decomposes at 58°C; is very soluble in water; pH of 0.1M aqueous solution is 8.9; moderately soluble in ethanol, 5.3 g/100mL.
2. Sodium acetate, CH3COONa, also abbreviated NaOAc , also sodium ethanoate, is the sodium salt of acetic acid, was made by the reaction of acetic acid with sodium carbonate. It is soluble in water but less so in alcohol. This colourless salt has a wide range of uses. Sodium acetate was used as a pH modifier for toning baths.
3. Sodium acetate is odorless or has a faint acetous odor. It effloresces in warm, dry air.

Physical properties

Anhydrous salt is a colorless crystalline solid; density 1.528 g/cm3; melts at 324°C; very soluble in water; moderately soluble in ethanol. The colorless crystalline trihydrate has a density 1.45 g/cm3; decomposes at 58°C; is very soluble in water; pH of 0.1M aqueous solution is 8.9; moderately soluble in ethanol, 5.3 g/100mL.

Occurrence

Acetic acid or acetates are present in most plant and animal tissues in small, but detectable amounts

Uses

Different sources of media describe the Uses of 127-09-3 differently. You can refer to the following data:
1. Sodium Acetate, Anhydrous is a source of acetic acid obtained as a granular powder. it has a solubility of 1 g in 2 ml of water.
2. Sodium acetate is a mordant in dyeing. Other applications are in photography, as an additive to food, in purification of glucose, in preservation of meat, in tanning, and as a dehydrating agent. In analytical chemistry it is used to prepare buffer solution. Sodium acetate can be used to preserve processed meats and it is often used in combination with other acid based preservatives like lactates and propionates. The typical inclusion level is 0.2 to 0.5%. Sodium acetate is also used in salad dressings and ready-to-eat meals.
3. Used as buffers. Acidity regulation (buffering) Sodium acetate mixed with acetic acid forms a pH buffer, which can be used to stabilise the pH of foods in the pH-range from 3 to 6. The table below gives indicative values of the composition needed to give a certain pH. The mixtures below can be diluted at least 10 times with minimum effect on pH, however, the stability decreases.

Preparation

Sodium acetate is prepared by reacting sodium hydroxide or sodium carbonate with acetic acid in aqueous solution. The solution is evaporated to obtain hydrated crystals of sodium acetate. NaOH + CH3COOH → CH3COONa + H2O Na2CO3 + CH3COOH → 2CH3COONa + CO2 + H2O

Definition

A white solid prepared by the neutralization of ethanoic acid with either sodium carbonate or sodium hydroxide. Sodium ethanoate reacts with sulfuric acid to form sodium hydrogensulfate and ethanoic acid; with sodium hydroxide it gives rise to sodium carbonate and methane. Sodium ethanoate is used in the dyeing industry.

Application

2 - 1 - Industrial Sodium acetate is used in the textile industry to neutralize sulfuric acid waste streams, and as a photoresist while using aniline dyes. It is also a pickling agent in chrome tanning, and it helps to retard vulcanization of chloroprene in synthetic rubber production. In processing cotton for disposable cotton pads, sodium acetate is used to eliminate the buildup of static electricity. 2 - 2 - Concrete longevity Sodium acetate is used to reduce the damage water can potentially do to concrete by acting as a concrete sealant, while also being environmentally benign and cheaper than the epoxy alternative that is usually employed for sealing concrete against water permeation. 2 - 3 - Food Sodium acetate may be added to foods as a seasoning. It may be used in the form of sodium diacetate — a 1:1 complex of sodium acetate and acetic acid, given the E-number E262. A frequent use is to impart a salt and vinegar flavor to potato chips. 2 - 4 - Buffer solution As the conjugate base of acetic acid, a solution of sodium acetate and acetic acid can act as a buffer to keep a relatively constant pH. 2 - 5 - Heating pad Sodium acetate is also used in consumer heating pads or hand warmers and is also used in hot ice. Sodium acetate trihydrate crystals melt at 58.4°C , (to 58°C ) dissolving in their water of crystallization. When they are heated to around 100°C, and subsequently allowed to cool, the aqueous solution becomes supersaturated. This solution is capable of cooling to room temperature with out forming crystals.

Synthesis

Different sources of media describe the Synthesis of 127-09-3 differently. You can refer to the following data:
1. For laboratory use, sodium acetate is very inexpensive, and is usually purchased instead of being synthesized. It is sometimes produced in a laboratory experiment by the reaction of acetic acid (ethanoic acid) with sodium carbonate, sodium bicarbonate, or sodium hydroxide. These reactions produce aqueous sodium acetate and water. Carbon dioxide is produced in the reaction with sodium carbonate and bicarbonate, and it leaves the reaction vessel as a gas (unless the reaction vessel is pressurized). This is the well-known "volcano" reaction between baking soda (sodium bicarbonate) and vinegar. CH3COOH + NaHCO3 → CH3COONa + H2O + CO2 Industrially, sodium acetate is prepared from glacial acetic acid and sodium hydroxide. CH3COOH + NaOH → CH3COONa + H2O.
2. Acetic acid plus sodium bicarbonate makes sodium acetate plus carbonic acid. Produced by the neutralization of acetic acid with sodium bicarbonate, or by treating calcium acetate with sodium sulfate and sodium bicarbonate.

Reactions

Sodium acetate can be used to form an ester with an alkyl halide such as bromo ethane: CH3COONa + Br CH2CH3→ CH3COOCH2CH3+ NaBr Caesium salts catalyze this reaction.

General Description

Sodium Acetate is reported to inhibit the growth of Listeria monocytogenes.

Reactivity Profile

When sodium acetate reacts with strong acids, irritating, noxious vapors of acetic acid are usually produced. Sodium acetate is sufficiently basic to catalyze the violent polymerization of diketene, perhaps as well as other reactive dimers that are susceptible to polymerization in the presence of a mild base.

Flammability and Explosibility

Nonflammable

Biological Activity

Commonly used laboratory reagent

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. A skin and eye irritant. Migrates to food from packagmg materials. Violent reaction with F2, m03, diketene. When heated to decomposition it emits toxic fumes of Na2O.

Purification Methods

Crystallise it from acetic acid and keep it under vacuum for 10hours at 120o. Alternatively, it is crystallised from aqueous EtOH, as the trihydrate. This material can be converted to anhydrous salt by heating slowly in a porcelain, nickel or iron dish, so that the salt liquefies. Steam is evolved and the mass again solidifies. Heating is now increased so that the salt melts again. (NB: if it is heated too strongly, the salt can char; avoid this.) After several minutes, the salt is allowed to solidify and is cooled to a convenient temperature (in a desiccator) before being powdered and bottled. The water content should now be less than 0.02%. [Beilstein 2 II 113, 2 III 184, 2 IV 109.]

InChI:InChI=1/C2H4O2.Na.3H2O/c1-2(3)4;;;;/h1H3,(H,3,4);;3*1H2/q;+1;;;/p-1

Synthetic route

sodium amidotrihydridoborate (148977-74-6) + acetic acid (64-19-7) → ammonia borane complex (10043-11-5) + sodium acetate (127-09-3)

Conditions	Yield
In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;	A 92% B n/a

acetic acid (64-19-7) → sodium acetate (127-09-3)

Conditions	Yield
With sodium methylate In methanol at 20℃;	91.85%
With KB-4P-2(Na) Equilibrium constant; exchange equilibrium constant;
With [D]-sodium hydroxide In water-d2 at 22.9℃;
With sodium methylate In methanol

sodium 2-oxopropane-1-sulfonate (16562-77-9) → sodium acetate (127-09-3) + methanesulfonic acid sodium salt (2386-57-4)

Conditions	Yield
With sodium hydroxide In water for 6h; Heating;	A 84% B 32%

Na5(IMo6O24)*99H2O + cobalt(II) diacetate tetrahydrate (6147-53-1) → Na3Co(IMo6O24)*14H2O + sodium acetate (127-09-3)

Conditions	Yield
With CH3COOH In water addn. of Co(OAc)2 to slurry of Mo salt, pH adjusted to 6 (HOAc), stirring (5 min), hot filtration, crystn. on slow evapn.; elem. anal.;	A 83% B n/a

sodium hydroxide (1310-73-2) + acetylene (74-86-2) → sodium acetate (127-09-3)

Conditions	Yield
With hydrogen In sodium hydroxide addn. of 4% C2H2/H2 mixt. to 20% aq. NaOH under pressure at 220-230°C;;	70%
With hydrogen In sodium hydroxide addn. of 4% C2H2/H2 mixt. to 20% aq. NaOH under pressure at 220-230°C;;	70%

sodium azide + 1,4-bis(imidazol-l-yl-methyl)benzene (56643-83-5) + cobalt(II) acetate (71-48-7, 917-69-1, 5931-89-5, 55881-15-7, 68931-68-0, 68931-69-1, 93029-27-7) → 2Co(2+)*3C3H3N2CH2C6H4CH2N2H3C3*4N3(1-)*6H2O=Co2(C3H3N2CH2C6H4CH2N2H3C3)3(N3)4*6H2O + sodium acetate (127-09-3)

Conditions	Yield
In methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;	A 66.2% B n/a

Na5(IMo6O24)*99H2O + copper(II) acetate monohydrate (6046-93-1) → Na3Cu(IMo6O24)*9H2O + sodium acetate (127-09-3)

Conditions	Yield
With CH3COOH In water addn. of Co(OAc)2 to slurry of Mo salt, pH adjusted to 6 (HOAc), stirring (5 min), hot filtration, crystn. on slow evapn.; elem. anal.;	A 65% B n/a

sodium azide + nickel diacetate (373-02-4, 14998-37-9, 33025-09-1, 94044-50-5, 98268-31-6) + 1,4-bis(imidazol-1-ylmethyl)-2,5-dimethylbenzene → 2Ni(2+)*3C3H3N2CH2C6H2(CH3)2CH2N2H3C3*4N3(1-)*4H2O=Ni2(C3H3N2CH2C6H2(CH3)2CH2N2H3C3)3(N3)4*4H2O + sodium acetate (127-09-3)

Conditions	Yield
In methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;	A 63.8% B n/a

acetamide (60-35-5) → 4,5-bis(aminomethyl)-3,6-bis(1-aminovinyl)cyclohexa-3,5-diene-1,2-dione (1198018-65-3) + sodium acetate (127-09-3)

Conditions	Yield
Stage #1: acetamide With sulfur dioxide; water at -15℃; Stage #2: With water; sodium carbonate at -10 - -5℃;	A 62% B n/a

sodium azide + 1,4-bis(imidazol-l-yl-methyl)benzene (56643-83-5) + nickel diacetate (373-02-4, 14998-37-9, 33025-09-1, 94044-50-5, 98268-31-6) → 2Ni(2+)*3C3H3N2CH2C6H4CH2N2H3C3*4N3(1-)*6H2O=Ni2(C3H3N2CH2C6H4CH2N2H3C3)3(N3)4*6H2O + sodium acetate (127-09-3)

Conditions	Yield
In methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;	A 56.8% B n/a

sodium azide + manganese(II) acetate (638-38-0, 993-02-2, 2180-18-9, 15411-95-7, 22981-23-3, 27004-39-3) + 1,4-bis(imidazol-1-ylmethyl)-2,5-dimethylbenzene → 2Mn(2+)*3C3H3N2CH2C6H2(CH3)2CH2N2H3C3*4N3(1-)*6H2O=Mn2(C3H3N2CH2C6H2(CH3)2CH2N2H3C3)3(N3)4*6H2O + sodium acetate (127-09-3)

Conditions	Yield
In methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;	A 56.7% B n/a

Upstream product

• 463-51-4 Ketene 
• 56-23-5 tetrachloromethane 
• 14036-06-7 diethoxymethyl acetate 
• 60-29-7 diethyl ether 
• 71-55-6 1,1,1-trichloroethane 
• 141-52-6 sodium ethanolate 
• 64-17-5 ethanol 
• 79-20-9 acetic acid methyl ester 
• 141-78-6 ethyl acetate 
• 74-86-2 acetylene 
• 2280-44-6 D-Glucose 
• 63839-88-3 1-(9H-fluoren-9-yl)ethyl acetate 
• 63839-89-4 Acetoxy-(9-fluorenyl)-phenyl-methan 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 70774-92-4 methyl 4,6-O-benzylidene-2-O-p-toluenesulphonyl-α-D-glucopyranoside 
• 542-59-6 2-hydroxyethyl acetate 
• 5371-52-8 2-hydroxytetrahydrofuran 
• 100-66-3 methoxybenzene 
• 93-89-0 benzoic acid ethyl ester 
• 6627-80-1 N-[1-(4-nitro-benzoyl)-vinyl]-acetamide 
• 637-64-9 tetrahydrofurfuryl acetate 
• 1666-11-1 bis(2,4-dinitrophenyl) diselenide 
• 102657-60-3 3-bromo-2-methyl-1.4-bis-(2.4.6-trimethyl-phenyl)-butene-(2t)-dione-(1.4) 
• 3173-13-5 1,5,1',5'-tetraphenyl-3,3'-ethanediyl-di-formazan 
• 932-16-1 N-methyl-2-acetylpyrrole 
• 6982-73-6 2-Acetyl-4,5-dimethyl-pyrrol 
• 6982-78-1 1-acetyl-2,3-dimethyl-pyrrole 
• 867132-26-1 1-(5-ethyl-pyrrol-2-yl)-ethanone 

Related news

Engineering fast dissolving Sodium acetate (cas 127-09-3) mediated crystalline solid dispersion of docetaxel09/28/2019

It is hypothesized that a novel crystalline solid dispersion (CSD) of docetaxel (C-DXT) can be engineered by dispersing native docetaxel (DXT, a BCS class II drug) in sodium acetate crystal (SA). DXT is dissolved in glacial acetic/SA solution and freeze-dried. The resulting C-DXT is characterize...detailed

Research PaperPorosity and density measurements of Sodium acetate (cas 127-09-3) trihydrate for thermal energy storage10/01/2019

Sodium acetate trihydrate (SAT) can be used as phase change material in latent heat storage with or without utilizing supercooling. The change of density from liquid to solid state leads to formation of cavities inside the bulk SAT during solidification. Samples of SAT which had solidified from ...detailed

Effect of embedding Sodium acetate (cas 127-09-3) trihydrate on the Ag anode in an electrical nucleation cell of a supercooled latent heat storage material09/26/2019

Electrical nucleation was investigated by using a Ag anode with sodium acetate trihydrate crystals embedded on the surface in a supercooled aqueous solution of sodium acetate (45–54 wt%) as a latent heat storage device. Rapid electrical nucleation was achieved by applying a direct-current volta...detailed

Effect of electro-activated solutions of Sodium acetate (cas 127-09-3) and sodium propionate on geosmin producing Streptomyces avermitilis strain09/25/2019

Electro-activated solutions of salts of weak organic acids are defined as novel potent disinfecting agents that can be used in the agri-food industry. The aim of the present work is to study and understand the destruction mechanism of electro-activated solutions of sodium acetate (EAA) and sodiu...detailed

A solar combi-system utilizing stable supercooling of Sodium acetate (cas 127-09-3) trihydrate for heat storage: Numerical performance investigation09/24/2019

To reduce the energy consumption of buildings significantly, a novel solar combi-system with short and long-term heat storage has been developed. A system prototype with 22.4 m2 (aperture) evacuated tubular collectors, a 735 L water tank and 4 phase change material (PCM) units each containing 15...detailed

ResearchEffect of dietary supplementation of Sodium acetate (cas 127-09-3) and calcium butyrate on milk fat synthesis in lactating dairy cows09/10/2019

ABSTRACTAcetate is a major source of energy and substrate for milk fat synthesis in the dairy cow. We recently reported a linear increase in milk fat yield and greater than a 30% net apparent transfer of acetate to milk fat with ruminal infusion of neutralized acetate. Additionally, ruminal acet...detailed

Structure and stability factor of aggregated particles in supercooled solution of Sodium acetate (cas 127-09-3) trihydrate09/09/2019

Aggregated particles in supercooled solution of sodium acetate trihydrate (SAT) are revealed to consist of crystals of sodium acetate (SA) by X-ray diffraction measurements performed on a premise of non-anisotropy of crystals in the solution. Model calculations of crystal growth of SA suggest th...detailed

Relevant articles and documents

A new, more efficient procedure for the preparation of potassium tris(malonto)cobaltate(III) dihydrate

A new, very efficient and elegant procedure for the preparation of potassium tris(malonato)cobaltate(III) dihydrate, starting from Co(OH)3 and potassium hydrogenmalonate, is presented. The most important advantages of this procedure, in comparison to the previously reported ones, are: a relatively short time required, saving of the reagents and solvents, and a very good yield of pure product. The identification of the obtained complex was carried out by elemental analyses, electronic absorption and IR spectroscopy. The spectral data are in accordance with the previously reported literature data. Analogous procedure was also preliminary tested for the preparation of the corresponding tris(oxalato)-and tris(succinato)cobaltate(III). Finally, the described complex can be used as a starting material for the preparation of one mixed ligand Co(III) complex.

Efficient Iridium Catalysts for Formic Acid Dehydrogenation: Investigating the Electronic Effect on the Elementary β-Hydride Elimination and Hydrogen Formation Steps

We report herein a series of Cp*Ir complexes containing a rigid 8-aminoquinolinesulfonamide moiety as highly efficient catalysts for the dehydrogenation of formic acid (FA). The complex [Cp*Ir(L)Cl] (HL = N-(quinolin-8-yl)benzenesulfonamide) displayed a high turnover frequency (TOF) of 2.97 × 104 h-1 and a good stability (>100 h) at 60 °C. Comparative studies of [Cp*Ir(L)Cl] with the rigid ligand and [Cp*Ir(L′)Cl] (HL′ = N-propylpypridine-2-sulfonamide) without the rigid aminoquinoline moiety demonstrated that the 8-aminoquinoline moiety could dramatically enhance the stability of the catalyst. The electron-donating ability of the N,N′-chelating ligand was tuned by functionalizing the phenyl group of the L ligand with OMe, Cl, and CF3 to have a systematical perturbation of the electronic structure of [Cp*Ir(L)Cl]. Experimental kinetic studies and density functional theory (DFT) calculations on this series of Cp*Ir complexes revealed that (i) the electron-donating groups enhance the hydrogen formation step while slowing down the β-hydride elimination and (ii) the electron-withdrawing groups display the opposite effect on these reaction steps, which in turn leads to lower optimum pH for catalytic activity compared to the electron-donating groups.

Synthesis and characterization of complexes of some hydroxyaryltellurium trichlorides with N-donor ligands

Twenty new complexes of hydroxyaryltellurium trichlorides derived from isomeric cresols and ortho-chlorophenol with pyridine (Py), 2,2′-bipyridyl (Bipy) and piperidine (Pip) have been synthesized and characterized by elemental analyses, conductance, cryoscopy, infrared and proton magnetic resonance studies. Pyridine and piperidine form RTeCl3.L and RTeCl3.2L complexes, whereas 2,2′-bipyridyl which acts as a bidentate ligand and gives only RTeCl3.L complexes. Conductance and cryoscopic measurements reflect their weak or 1:1 electrolytic behaviour in solution of nitrobenzene, acetonitrile and acetone. Spectral studies indicate the linkage of these ligand molecules to the tellurium atom of the hydroxyaryltellurium group through nitrogen atoms. A square-pyramidal structure is suggested for RTeCl3.Py and RTeCl3.Pip, whereas 1:2 complexes of pyridine and piperidine along with RTeCl3.Bipy, have octahedral stereochemistry.

Interaction of cobalt(II) and copper(II) with polyoxometallates. Structure of Na3Co[IMo6O24]. 14H2O

Cobalt(II) and copper(II) complexes with the ligand anion [IMo6O24]5- (periodate 6-molybdoanion) of the general formula Na3M[IMo6O24].nH2O (where M = Co, Cu) have been prepared by the reaction of the corresponding metal salts with the ligand in aqueous media (pH = 6). The complexes were characterised by elemental and thermogravimetric analyses, spectral data (IR, UV-vis). The EPR spectrum of a copper(II) powder sample was recorded at both room temperature and 12 K indicating a weakly distorted octahedral copper(II) stereochemistry. The crystal structure of Na3CO[IMo6O24]. 14H2O has been determined by single-crystal X-ray diffraction technique.

Selective formation of lactate by oxidation of 1,2-propanediol using gold palladium alloy supported nanocrystals

The use of bio-renewable resources, such as glycerol, a by-product from bio-diesel manufacture, can provide a viable way to make valuable products using greener technology. In particular, glycerol can be reduced to give 1,2-propanediol that can then be se

No contribution of an inductive effect to secondary deuterium isotope effects on acidity

Effect and cause: Secondary deuterium isotope effects on the acidity of the deuterated compounds 1-4 were measured by using an NMR titration method applicable to a mixture and capable of very high accuracy. Variable-temperature experiments show that these isotope effects are due only to changes in vibrational frequencies. These findings refute an inductive origin for these isotope effects. Copyright

MECHANISM OF CHLORAMINE-T OXIDATION OF METHYL VINYL KETONE AND ISOPROPYL METHYL KETONE IN AQUEOUS ALKALINE MEDIA

The oxidation kinetics of methyl vinyl ketone and isopropyl methyl ketone by chloramine-T in aqueous alkaline solutions show first-order dependence on chloramine-T, both substrates and alkali.No effect of p-toluenesulphonamide was evident.Observed stoichiometry, negligible effect of ionic strength and a positive dielectric effect point to a mechanism involving interaction of enolate anions with chloramine-T in the rate determining step.Activation parameters and the isolation of the product formaldehyde are in agreement with the proposed mechanism.

Photoluminescence as a valuable tool in the optical characterization of acetaminophen and the monitoring of its photodegradation reactions

In this work, new evidence for the photodegradation reactions of acetaminophen (AC) is reported by photoluminescence (PL), Raman scattering and FTIR spectroscopy. Under excitation wavelength of 320 nm, AC shows a PL band in the spectral range of 340–550 nm, whose intensity decreases by exposure to UV light. The chemical interaction of AC with the NaOH solutions, having the concentration ranging between 0.001 and 0.3 M, induces a gradual enhancement of the photoluminescence excitation (PLE) and PL spectra, when the exposure time of samples at the UV light increases until 140 min, as a result of the formation of p-aminophenol and sodium acetate. This behavior is not influenced by the excipients or other active compounds in pharmaceutical products as demonstrated by PLE and PL studies. Experimental arguments for the obtaining of p-aminophenol and sodium acetate, when AC has interacted with NaOH, are shown by Raman scattering and FTIR spectroscopy.

Method for preparing anhydrous sodium acetate based on the generation between acetic acid and sodium carbonate

The invention discloses a method for preparing anhydrous sodium acetate based on the generation between acetic acid and sodium carbonate in the technology field of preparing anhydrous sodium acetate, the requirement materials of anhydrous sodium acetate based on the generation between acetic acid and sodium carbonate is given below:440-520g of acetic acid; 180-220g of sodium carbonate. a stainless steel reaction kettle,a cooling equipment; a drying oven, the method for preparing anhydrous sodium acetate comprises: S1: preparation; S2: stirring; S3: heating; S4: crystallization; S5:drying for the finished product; S6: the steps of filling, the generation between acetic acid and sodium carbonate is simple in formula, the atmospheric environment pollution is reduced as far as possible during preparation,the preparation of anhydrous sodium acetate is achieved by the steps of solution, heating, cooling and drying etc., simple in steps with less energy consumption and large amount of the prepared anhydrous sodium acetate,and different levels of anhydrous sodium acetate and be got by adjusting the different proportions, which can be respectively used in medicine, food and industry.