131-56-6 Usage
Description
2,4-Dihydroxybenzophenone is a yellow crystalline powder that serves as a metabolite of Benzophenone, a compound utilized in the production of antihistamines, hypnotics, and insecticides. It is known for its chemical properties and versatile applications across various industries.
Uses
Used in Pharmaceutical Industry:
2,4-Dihydroxybenzophenone is used as a metabolite for the manufacturing of antihistamines, hypnotics, and insecticides, contributing to the development of essential medications for various health conditions.
Used in Paints and Plastics Industry:
As an ultraviolet light absorber, 2,4-Dihydroxybenzophenone is employed in the production of paints and plastics to enhance their durability and protect them from the harmful effects of UV radiation.
Used in Dye Industry:
2,4-Dihydroxybenzophenone is used as a coupling agent for the preparation of novel mordent and disperse azo dyes, which are synthesized by the coupling of various diazo solutions of aromatic amines with the compound.
Used in Polymer Industry:
The compound is utilized in the synthesis of ultraviolet absorbing monomers by reacting with glycidyl acrylate and glycidyl methacrylate. Additionally, it is used in the development of new polymerizable stabilizers, such as 4-benzoyl-2-(α-piperidino-2-chlorobenzyl)-3-hydroxyphenyl acrylate (BPBHA) and its corresponding methacrylate (BPBHMA), as well as 2-hydroxy-4-(3-methacryloxy-2-hydroxylpropoxy) benzophenone (BPMA), which is synthesized using 2,4-dihydroxybenzophenone (UV-0) and glycidyl methacrylate (GMA). These stabilizers play a crucial role in enhancing the stability and performance of polymers in various applications.
Preparation
Obtained by condensation of benzanilide with resorcinol in the presence of zinc chloride and phosphorous oxychloride at 130–140° for 1 h (25%).
Contact allergens
BZP-1 is used, for example, in paints, plastics, and nail
varnishes.
Safety Profile
Poison by intravenous
and intraperitoneal routes. Mildly toxic by
ingestion. An eye irritant. When heated to
decomposition it emits acrid smoke and
irritating fumes.
Purification Methods
Recrystallise it from MeOH. [Beilstein 8 IV 2442.]
Check Digit Verification of cas no
The CAS Registry Mumber 131-56-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 131-56:
(5*1)+(4*3)+(3*1)+(2*5)+(1*6)=36
36 % 10 = 6
So 131-56-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H10O3/c14-10-6-7-11(12(15)8-10)13(16)9-4-2-1-3-5-9/h1-8,14-15H
131-56-6Relevant articles and documents
Efficient microwave-assisted direct C-benzoylation of phenols and naphthols with benzoic acid catalyzed by bismuth triflate under solvent-free or ionic liquid conditions
Tran, Phuong Hoang,Phung, Huy Quang,Duong, Minh Nhat,Pham-Tran, Nguyen-Nguyen
, p. 1558 - 1563 (2017)
An efficient and simple route for the synthesis of ortho-hydroxyaryl ketones has been developed. The microwave-assisted direct C-benzoylation of phenols and naphthols in the presence of metal triflates afforded the corresponding ortho-hydroxyaryl ketones in moderate to excellent yields. Bismuth triflate showed the best catalytic performance compared to other metal triflates. The protocol has advantages including short reaction times, high chemoselectivity towards C-acylation, and simple work-up. Additionally, bismuth triflate can be easily recovered and reused several times without significant loss of catalytic performance.
Selective Oxidation of Alkylarenes to the Aromatic Ketones or Benzaldehydes with Water
Du, Jihong,Duan, Baogen,Liu, Kun,Liu, Renhua,Yu, Feifei,Yuan, Yongkun,Zhang, Chenyang,Zhang, Jin
supporting information, (2022/02/09)
Here a palladium-catalyzed oxidation method for converting alkylarenes into the aromatic ketones or benzaldehydes with water as the only oxygen donor is reported. This C-H bond oxidation functionalization does not require other oxidants and hydrogen accep
A SUNSCREEN FORMULATION
-
Paragraph 0045-0046; 0049-0050, (2020/06/10)
Disclosed herein are the synthesis of new classes of sunscreen agents, the usage of such sunscreen agents in sunscreen formulations aiming at reduction of sunscreen agents' skin penetration, and a formulation technology using existing sunscreen agents aiming at reduction of sunscreen agents's kin penetration, therefore improving the bio-safety of the sunscreen products.