471-25-0Relevant articles and documents
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Grignard,Lapayre,Tcheoufaki
, (1929)
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Synthetic method of propiolic acid
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Paragraph 0020-0029, (2020/07/24)
The invention discloses a synthetic method of propiolic acid. The method comprises the following steps of: putting calcium carbide, a hydrogen donor, a solvent, a catalyst and an auxiliary agent intoa reaction kettle, introducing carbon dioxide into the reaction kettle, and heating and pressurizing to react, wherein the reaction temperature is 30-80 DEG C, the reaction pressure is 1-6 MPa, and the reaction time is 12-24 hours; separating a liquid and a hydrogen donor from the mixture after the reaction, and acidifying the liquid mixture to obtain a product. The propiolic acid synthesis methoddisclosed by the invention is relatively environment-friendly and low in production cost.
Gold-catalyzed formal [4π+2π]-cycloadditions of tert-butyl propiolates with aldehydes and ketones to form 4H-1,3-dioxine derivatives
Karad, Somnath Narayan,Chung, Wei-Kang,Liu, Rai-Shung
supporting information, p. 13004 - 13007 (2015/08/06)
Gold-catalyzed formal hetero-[4π+2π] cycloadditions of tert-butyl propiolates with carbonyl compounds proceeded efficiently to yield 4H-1,3-dioxine derivatives over a wide scope of substrates. With acetone as a promoter, gold-catalyzed cycloadditions of these propiolate derivatives with enol ethers led to the formation of atypical [4+2]-cycloadducts with skeletal rearrangement.