55676-21-6

Basic information

• Product Name: 3-ACETYL-2-CHLOROPYRIDINE
• Synonyms: 1-(2-chloro-3-pyridinyl)-1-ethanone;2-chloro-3-acetylpyridine;1-(2-chloro-3-pyridinyl)ethanone;1-(2-chloro-3-pyridinyl)ethanone(SALTDATA: FREE);1-(2-chloropyridin-3-yl)ethan-1-one;1-(2-Chloropyridin-3-yl)ethan-1-one, 2-Chloro-3-ethanoylpyridine;3-Acetyl-2-chloropyridine 95%;Ethanone, 1-(2-chloro-3-pyridinyl)-
• CAS NO: 55676-21-6
• Molecular Formula: C₇H₆ClNO
• Molecular Weight: 155.58
• EINECS: -0
• Product Categories: pharmacetical;Pyridine series;alkyl chloride
• Mol File: 55676-21-6.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 114°C/15mmHg(lit.)
• Flash Point: >110℃
• Appearance: /
• Density: 1.233 g/cm³
• Vapor Pressure: 0.06mmHg at 25°C
• Refractive Index: 1.5440-1.5480
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -1.65±0.10(Predicted)
• CAS DataBase Reference: 3-ACETYL-2-CHLOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETYL-2-CHLOROPYRIDINE(55676-21-6)
• EPA Substance Registry System: 3-ACETYL-2-CHLOROPYRIDINE(55676-21-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 55676-21-6(Hazardous Substances Data)

Usage

Uses

3-Acetyl-2-chloropyridine is a reagent used in the synthesis of Volitinib, a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor as an anti-cancer agent.

InChI:InChI=1/C7H6ClNO/c1-5(10)6-3-2-4-9-7(6)8/h2-4H,1H3

Upstream product

• 49609-84-9 2-Chloronicotinoyl chloride 
• 2942-59-8 2-chloronicotinic acid 
• 79-37-8 oxalyl dichloride 
• 594-27-4 tetramethylstannane 
• 144-55-8 sodium hydrogencarbonate 
• 488149-34-4 2-chloro-N-methoxy-N-methyl-pyridine-3-carboxamide 
• 75-16-1 methylmagnesium bromide 
• 917-54-4 methyllithium 
• 676-58-4 methylmagnesium chloride 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 149226-59-5 diethyl 2-(2-chloronicotinoyl)-malonate 
• 109-09-1 2-chloropyridine 
• 350-03-8 methyl-3-pyridylketone 
• 40134-18-7 methyl 2-chloropyridine-3-carboxylate 

Downstream Products

• 174180-77-9 tert-butyl 3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylate 
• 1027990-21-1 3-(bromomethyl)-1H-pyrazolo[3,4-b]pyridine 
• 1392482-84-6 3-(4-carboxy-benzyl)-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridine-2-carboxylic acid methyl ester 
• 1392482-81-3 4-[(E)-3-oxo-3-(2-phenylamino-pyridin-3-yl)-propenyl]-benzoic acid methyl ester 
• 1392482-82-4 4-[3-oxo-3-(2-phenylamino-pyridin-3-yl)-propyl]-benzoic acid methyl ester 
• 1392482-83-5 4-{3-[2-(methoxyoxalyl-phenyl-amino)-pyridin-3-yl]-3-oxo-propyl}benzoic acid methyl ester 
• 1402345-15-6 3-methoxy-4-[(E)-3-oxo-3-(2-phenylamino-pyridin-3-yl)-propenyl]-benzoic acid methyl ester 
• 1402345-16-7 3-methoxy-4-[3-oxo-3-(2-phenylamino-pyridin-3-yl)-propyl]-benzoic acid methyl ester 
• 1402345-17-8 3-methoxy-4-{3-[2-(methoxyoxalyl-phenyl-amino)-pyridin-3-yl]-3-oxo-propyl}-benzoic acid methyl ester 
• 1402345-18-9 3-(2-methoxy-4-methoxycarbonyl-benzyl)-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridine-2-carboxylic acid methyl ester 
• 1402345-19-0 3-(4-carboxy-2-methoxy-benzyl)-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridine-2-carboxylic acid methyl ester 
• 1402345-20-3 3-fluoro-4-[(E)-3-oxo-3-(2-phenylamino-pyridin-3-yl)-propenyl]-benzoic acid methyl ester 
• 1402345-21-4 3-fluoro-4-[3-oxo-3-(2-phenylamino-pyridin-3-yl)-propyl]-benzoic acid methyl ester 
• 1402345-22-5 3-fluoro-4-{3-[2-(methoxyoxalyl-phenyl-amino)-pyridin-3-yl]-3-oxo-propyl}-benzoic acid methyl ester 

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