628-20-6

Basic information

• Product Name: 4-Chlorobutyronitrile
• Synonyms: GAMMA-CHLOROPROPYL CYANIDE;4-CHLOROBUTYRONITRILE;4-CHLOROBUTANENITRILE;4-chloro-butanenitril;4-chloro-butyronitril;Butyronitrile, 4-chloro-;gamma-Chlorobutyronitrile;4-CHLOROBUTYRONITRILE 99% (GC)
• CAS NO: 628-20-6
• Molecular Formula: C₄H₆ClN
• Molecular Weight: 103.55
• EINECS: 211-031-6
• Product Categories: Halogen compounds;Miscellaneous;Aliphatics;C1 to C5;Cyanides/Nitriles;Nitrogen Compounds;API Intermediate
• Mol File: 628-20-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 195-197 °C(lit.)
• Flash Point: 185 °F
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 1.158 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.442(lit.)
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate (Slightly)
• Water Solubility: immiscible
• BRN: 1633582
• CAS DataBase Reference: 4-Chlorobutyronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorobutyronitrile(628-20-6)
• EPA Substance Registry System: 4-Chlorobutyronitrile(628-20-6)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25-36/37/38
• Safety Statements: 45-7-36/37/39
• RIDADR: UN 3276 6.1/PG 3
• WGK Germany: 3
• RTECS: ET9020000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 628-20-6(Hazardous Substances Data)

Usage

Chemical Properties

Clear Colourless Liquid

Uses

4-Chlorobutyronitrile (cas# 628-20-6) is a compound useful in organic synthesis.

General Description

A liquid. Flash point 85°F. Density about 9.7 lb / gal and practically insoluble in water (2 parts/100 parts water). Hence sinks in water. Vapors are heavier than air. Irritates the eyes but not to the skin. Releases hydrogen chloride, hydrogen cyanide, and hydrogen bromide gases when heated or involved in a fire.

Air & Water Reactions

Highly flammable. Practically insoluble in water.

Reactivity Profile

4-Chlorobutyronitrile may attack some forms of plastics [USCG, 1999].

Health Hazard

Chemical is moderately toxic. Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Can penetrate the skin on prolonged contact; only slightly irritating.

Fire Hazard

Special Hazards of Combustion Products: Toxic and irritating hydrogen cyanide, hydrogen bromide, and hydrogen chloride may form in fires.

InChI:InChI=1/C4H6ClN/c5-3-1-2-4-6/h1-3H2

Synthetic route

1-chloro-4,4-dihydroxy-4-butylamine → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With aluminum oxide; calcium hydroxide; 2-hydroxynitrobenzene In cyclohexane at 77 - 97℃; for 5.5h; Temperature; Reflux;	92%

4-chlorobutyramide (2455-04-1) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With formaldehyd; formic acid; acetonitrile for 12h; Heating;	87%

2-((cyclobutylideneamino)oxy)-2-methylpropanoic acid → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With N-chloro-succinimide; potassium acetate; 9-(2-mesityl)-10-methylacridinium perchlorate In acetonitrile at 20℃; for 1h; Irradiation; Sealed tube; Inert atmosphere;	59%

5-chloro-valeric acid (1119-46-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With trifluoroacetic acid; trifluoroacetic anhydride; sodium nitrite at 20℃; nitrosative cleavage;	57%

propyl cyanide (109-74-0) → 3-chlorobutyronitrile (53778-71-5) + 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With chlorine Irradiation.mit UV-Licht;
With sodium persulfate; copper dichloride In water at 85 - 90℃; for 10h; Yield given. Yields of byproduct given;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;

hydroxymethyl propionamide (927-60-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With thionyl chloride; benzene
With trichlorophosphate; benzene
With phosphorus trichloride

ethanol (64-17-5) + sodium cyanide (143-33-9) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6) + 4-bromobutanenitrile (5332-06-9)

ethanol (64-17-5) + potassium cyanide (151-50-8) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6) + Glutaronitrile (544-13-8)

sodium cyanide (143-33-9) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6) + Glutaronitrile (544-13-8)

Conditions	Yield
With methanol

potassium cyanide (151-50-8) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With ethanol
With ethanol; water Alkohol abdestillieren,Wasser zum Rueckstand geben,abgeschiedene Oelschicht abheben und fraktionieren;

1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6)

4-butanolide (96-48-0) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
(i) liq. NH3, (ii) SOCl2; Multistep reaction;

tetraethylammoniumcyanide (13435-20-6) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
In dichloromethane

2,4-dichlorobutanenitrile (77100-86-8) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With acetic acid; zinc for 2h; Yield given;

1,3-chlorobromopropane (109-70-6) + alcoholic KCN → 4-Chlorobutyronitrile (628-20-6)

propyl cyanide (109-74-0) + chlorine (7782-50-5) → 3-chlorobutyronitrile (53778-71-5) + 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
mit UV-Licht in der Dampfphase.Irradiation;

propyl cyanide (109-74-0) + chlorine (7782-50-5) → 3-chlorobutyronitrile (53778-71-5) + 4-Chlorobutyronitrile (628-20-6) + 2-chlorobutyronitrile (4158-37-6)

Conditions	Yield
at 450℃; Dampfphase;

propyl cyanide (109-74-0) → 4-Chlorobutyronitrile (628-20-6) + 2-chloro-butyronitrile and 3-chloro-butyronitrile

Conditions	Yield
With chlorine at 450℃;

4-Chlorobutyronitrile (628-20-6) + sodium thiomethoxide (5188-07-8) → 4-(methylthio)butyronitrile (59121-24-3)

Conditions	Yield
In ethanol at 20℃; for 25h; Inert atmosphere; Cooling with ice;	100%
In ethanol
In ethanol at 25℃; for 15h;

4-Chlorobutyronitrile (628-20-6) + tert-butyl N-(benzyloxy)carbamate (79722-21-7) → 4-[N-(tert-butyloxycarbonyl)benzyloxyamino]butyronitrile (489452-95-1)

Conditions	Yield
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere; Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 80℃; for 6h;	100%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 70℃; for 18h; Inert atmosphere;	98%
With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 60 - 70℃; for 5h;	80%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 0℃; Inert atmosphere; Stage #2: 4-Chlorobutyronitrile In N,N-dimethyl-formamide at 85℃; Inert atmosphere;	70%
With sodium hydride; potassium iodide In N,N-dimethyl-formamide

4-Chlorobutyronitrile (628-20-6) + (S)-(-)-[1-phenylethyl]-1H-imidazole (129696-60-2) → 3-(3-cyanopropyl)-1-((1S)-1-phenylethyl)-1H-imidazol-3-ium chloride (1253119-37-7)

Conditions	Yield
In acetonitrile Reflux;	100%

morpholine (110-91-8) + 4-Chlorobutyronitrile (628-20-6) → 3-(morpholin-4-yl)-butanenitrile (5807-11-4)

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 72h;	99%
In toluene for 7h; Reflux;	65%
at 20℃;	63%

4-Chlorobutyronitrile (628-20-6) → cyclopropropanecarbonitrile (5500-21-0)

Conditions	Yield
With hydrogenchloride; sodium hydroxide; sodium chloride In water; dimethyl sulfoxide	98%
With sodium hydride In ethylene glycol; mineral oil at 20 - 80℃; for 0.5h; Solvent; Reagent/catalyst;	97.2%
With potassium tert-butylate In tetrahydrofuran at -30℃; for 0.333333h;	89%

4-Chlorobutyronitrile (628-20-6) + methyl N-tosylanthranilate (50998-74-8) → methyl 2-{(3-cyanopropyl)[(4-methylphenyl)sulfonyl]amino}benzoate (105895-93-0)

Conditions	Yield
With potassium carbonate; potassium iodide In butanone for 12h; Heating;	98%
With potassium carbonate; potassium iodide In acetone for 168h; Heating;	95%
With potassium carbonate; potassium iodide In butanone for 12h; Reflux;	80.1%

4-Chlorobutyronitrile (628-20-6) + [1(R)-methyl-3-[(phenylmethyl)amino]propyl]carbamic acid, 1,1-dimethylethyl ester (170367-70-1) → 3-[(3-cyanopropyl)(phenylmethyl)amino-1(R)-methylpropyl]carbamic acid, 1,1-dimethylethyl ester (170367-71-2)

Conditions	Yield
With sodium carbonate; potassium iodide In butan-1-ol for 20h; Alkylation; Heating;	98%

4-Chlorobutyronitrile (628-20-6) + N-(2,4,6-trimethylphenyl)imidazole (25364-44-7) → 1-(2,4,6-trimethylphenyl)-3-(butylnitrile)imidazolium chloride (1247011-82-0)

Conditions	Yield
In 1,2-dimethoxyethane for 72h; Reflux; Inert atmosphere;	98%
In 1,2-dimethoxyethane Inert atmosphere; Heating;	98%

4-Chlorobutyronitrile (628-20-6) → 2-bromo-4-chlorobutyronitrile

Conditions	Yield
With triphenyl phosphite; bromine at 80℃; for 4h; Reagent/catalyst;	98%

4-Chlorobutyronitrile (628-20-6) + dimethylsilicon dichloride (75-78-5) → (3-cyanopropyl)dimethylsilyl chloride (18156-15-5)

Conditions	Yield
With magnesium; ethylene dibromide; manganese(ll) chloride In tetrahydrofuran at 65℃; for 2h; Inert atmosphere;	96.1%
Stage #1: 4-Chlorobutyronitrile With sodium In toluene at 108 - 110℃; for 3h; Stage #2: dimethylsilicon dichloride In toluene at 40 - 45℃; for 4h; Temperature;

4-Chlorobutyronitrile (628-20-6) + 1-(2-Methoxyphenyl)piperazine (35386-24-4) → 4‐[4‐(2‐methoxyphenyl)piperazin‐1‐yl]butannitrile (25024-99-1)

Conditions	Yield
With cesium hydroxide; sodium iodide at 60℃; for 1.33333h; Microwave irradiation; Neat (no solvent); chemoselective reaction;	96%

4-Chlorobutyronitrile (628-20-6) + N-p-toluenesulfonyl-4-chloro-anthranilic acid methyl ester (29247-79-8) → methyl 4-chloro-2-(N-tosyl-3-cyanopropylamino)benzoate (105896-01-3)

Conditions	Yield
With potassium carbonate; potassium iodide In acetone for 168h; Heating;	95%

4-Chlorobutyronitrile (628-20-6) + N-[N-(tert-Butyloxycarbonyl)-3-aminopropyl]benzylamine (90914-08-2) → N-[N-(tert-Butoxycarbonyl)-3-aminopropyl]-N-(3-cyanopropyl)benzylamine (90914-11-7)

Conditions	Yield
With sodium carbonate; potassium iodide In butan-1-ol for 48h; Heating;	95%

4-Chlorobutyronitrile (628-20-6) + thiophenol (108-98-5) → 4-(phenylthio)butanenitrile (35756-39-9)

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 48h; Inert atmosphere;	95%
With triethylamine In N,N-dimethyl-formamide at 25℃;
With sodium methylate; sodium iodide 1.) methanol, 1 h, 2.) reflux, 12 h; Yield given. Multistep reaction;

salicylonitrile (611-20-1) + 4-Chlorobutyronitrile (628-20-6) → 4-(2-cyanophenoxy)butanenitrile

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 4h; Heating;	95%

4-Chlorobutyronitrile (628-20-6) + 1,2,3,4-tetrahydro-4-methylspiro (127934-39-8) → N-(γ-cyanopropyl)-3,4-dihydro-4-methylspiro[quinoline-2,1'-cyclohexane] (522592-78-5)

Conditions	Yield
With sodium carbonate; potassium iodide In butan-1-ol Heating;	95%

1-methyl-1H-imidazole (616-47-7) + 4-Chlorobutyronitrile (628-20-6) → 1-(3'-cyanopropyl)-3-methylimidazolium chloride

Conditions	Yield
at 80℃; for 24h;	95%
at 70℃; for 48h; Neat (no solvent); Sealed vial;	92%
at 80℃; for 24h;	82%
Heating;	78%
at 79.84℃; for 48h;

4-Chlorobutyronitrile (628-20-6) + trans-hydridochloro-di-{1,2-bis(diphenylphosphino)ethane}iron(II) (19392-93-9, 32490-70-3) → trans-[FeH(4-chlorobutyronitrile)(dppe)2]Cl (252659-30-6)

Conditions	Yield
In further solvent(s) Ar-atmosphere; stirring in ClCH2CH2CH2CN for 1 h; filtration, solvent removal (vac.), washing (Et2O); elem. anal.;	95%

methanol (67-56-1) + 4-Chlorobutyronitrile (628-20-6) → methyl 3-chloropropanimidate hydrochloride (77570-15-1)

Conditions	Yield
With hydrogenchloride In diethyl ether at 20℃; for 4h;	94%
With hydrogenchloride In diethyl ether at -20℃; for 24h;	90%
With hydrogenchloride In diethyl ether at 0℃; for 24h;	70%
With hydrogenchloride In diethyl ether at -20 - 0℃; for 28h;

1-chloro-4,4-dihydroxy-4-butylamine → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With aluminum oxide; calcium hydroxide; 2-hydroxynitrobenzene In cyclohexane at 77 - 97℃; for 5.5h; Temperature; Reflux;	92%

4-chlorobutyramide (2455-04-1) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With formaldehyd; formic acid; acetonitrile for 12h; Heating;	87%

2-((cyclobutylideneamino)oxy)-2-methylpropanoic acid → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With N-chloro-succinimide; potassium acetate; 9-(2-mesityl)-10-methylacridinium perchlorate In acetonitrile at 20℃; for 1h; Irradiation; Sealed tube; Inert atmosphere;	59%

5-chloro-valeric acid (1119-46-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With trifluoroacetic acid; trifluoroacetic anhydride; sodium nitrite at 20℃; nitrosative cleavage;	57%

propyl cyanide (109-74-0) → 3-chlorobutyronitrile (53778-71-5) + 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With chlorine Irradiation.mit UV-Licht;
With sodium persulfate; copper dichloride In water at 85 - 90℃; for 10h; Yield given. Yields of byproduct given;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;

hydroxymethyl propionamide (927-60-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With thionyl chloride; benzene
With trichlorophosphate; benzene
With phosphorus trichloride

ethanol (64-17-5) + sodium cyanide (143-33-9) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6) + 4-bromobutanenitrile (5332-06-9)

ethanol (64-17-5) + potassium cyanide (151-50-8) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6) + Glutaronitrile (544-13-8)

sodium cyanide (143-33-9) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6) + Glutaronitrile (544-13-8)

Conditions	Yield
With methanol

potassium cyanide (151-50-8) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With ethanol
With ethanol; water Alkohol abdestillieren,Wasser zum Rueckstand geben,abgeschiedene Oelschicht abheben und fraktionieren;

1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6)

4-butanolide (96-48-0) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
(i) liq. NH3, (ii) SOCl2; Multistep reaction;

tetraethylammoniumcyanide (13435-20-6) + 1,3-chlorobromopropane (109-70-6) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
In dichloromethane

2,4-dichlorobutanenitrile (77100-86-8) → 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
With acetic acid; zinc for 2h; Yield given;

1,3-chlorobromopropane (109-70-6) + alcoholic KCN → 4-Chlorobutyronitrile (628-20-6)

propyl cyanide (109-74-0) + chlorine (7782-50-5) → 3-chlorobutyronitrile (53778-71-5) + 4-Chlorobutyronitrile (628-20-6)

Conditions	Yield
mit UV-Licht in der Dampfphase.Irradiation;

propyl cyanide (109-74-0) + chlorine (7782-50-5) → 3-chlorobutyronitrile (53778-71-5) + 4-Chlorobutyronitrile (628-20-6) + 2-chlorobutyronitrile (4158-37-6)

Conditions	Yield
at 450℃; Dampfphase;

propyl cyanide (109-74-0) → 4-Chlorobutyronitrile (628-20-6) + 2-chloro-butyronitrile and 3-chloro-butyronitrile

Conditions	Yield
With chlorine at 450℃;

4-Chlorobutyronitrile (628-20-6) + sodium thiomethoxide (5188-07-8) → 4-(methylthio)butyronitrile (59121-24-3)

Conditions	Yield
In ethanol at 20℃; for 25h; Inert atmosphere; Cooling with ice;	100%
In ethanol
In ethanol at 25℃; for 15h;

4-Chlorobutyronitrile (628-20-6) + tert-butyl N-(benzyloxy)carbamate (79722-21-7) → 4-[N-(tert-butyloxycarbonyl)benzyloxyamino]butyronitrile (489452-95-1)

Conditions	Yield
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere; Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 80℃; for 6h;	100%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 70℃; for 18h; Inert atmosphere;	98%
With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 60 - 70℃; for 5h;	80%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 0℃; Inert atmosphere; Stage #2: 4-Chlorobutyronitrile In N,N-dimethyl-formamide at 85℃; Inert atmosphere;	70%
With sodium hydride; potassium iodide In N,N-dimethyl-formamide

4-Chlorobutyronitrile (628-20-6) + (S)-(-)-[1-phenylethyl]-1H-imidazole (129696-60-2) → 3-(3-cyanopropyl)-1-((1S)-1-phenylethyl)-1H-imidazol-3-ium chloride (1253119-37-7)

Conditions	Yield
In acetonitrile Reflux;	100%

morpholine (110-91-8) + 4-Chlorobutyronitrile (628-20-6) → 3-(morpholin-4-yl)-butanenitrile (5807-11-4)

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 72h;	99%
In toluene for 7h; Reflux;	65%
at 20℃;	63%

4-Chlorobutyronitrile (628-20-6) → cyclopropropanecarbonitrile (5500-21-0)

Conditions	Yield
With hydrogenchloride; sodium hydroxide; sodium chloride In water; dimethyl sulfoxide	98%
With sodium hydride In ethylene glycol; mineral oil at 20 - 80℃; for 0.5h; Solvent; Reagent/catalyst;	97.2%
With potassium tert-butylate In tetrahydrofuran at -30℃; for 0.333333h;	89%

Upstream product

• 109-74-0 propyl cyanide 
• 109-70-6 1.3-chlorobromopropane 
• 1119-46-6 5-chloro-valeric acid 
• 2455-04-1 4-chlorobutyramide 
• 77100-86-8 2,4-dichlorobutanenitrile 
• 13435-20-6 tetraethylammoniumcyanide 
• 96-48-0 4-butanolide 
• 151-50-8 potassium cyanide 
• 143-33-9 sodium cyanide 
• 64-17-5 ethanol 
• 927-60-6 hydroxymethyl propionamide 
• 7782-50-5 chlorine 

Downstream Products

• 13858-50-9 4-diisopropylamino-butyronitrile 
• 872-34-4 2-imino-pyrrolidine 
• 39580-37-5 (Z)-3-(4-Bromo-phenyl)-3-hydroxy-dithioacrylic acid 3-cyano-propyl ester 
• 38759-54-5 3β-(4'-Chlorbutyramido)-5-cholesten 
• 38759-58-9 N-Benzhydryl-4-chlorbutyramid 
• 161452-08-0 N-(tert-butoxycarbonyl)-N-(3-cyanopropyl)mesitylenesulfonamide 
• 134722-23-9 methyl O-(3-Cyanopropyl)salicylate 
• 58039-14-8 4-[8-fluoro-5-(4-fluoro-phenyl)-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-2-yl]-butyronitrile 
• 96682-41-6 4-(3,4-dimethoxyphenylamino)butyronitrile 
• 78217-67-1 N,N-Bis(3-cyanopropyl)-benzylamine 
• 71510-64-0 N-(3-cyanopropyl)benzylamine 
• 7235-16-7 2,3,4,9-tetrahydro-1H-fluoren-1-one 
• 134330-66-8 Ethyl S-(3-cyanopropyl)thiosalicylate 
• 64605-33-0 2-amino-4-chloro-γ-chlorobutyrophenone 

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