695-06-7Relevant articles and documents
SYNTHESIS OF γ-LACTONES BY THE HYDROBORYLATION AND OXIDATION OF HOMOALLYLIC ALCOHOLS
Hao, Nguyen Cong,Mavrov, M. V.,Chrelashvili, Z. G.,Serebryakov, E. P.
, p. 1042 - 1044 (1988)
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Calcium(II)- And Triflimide-Catalyzed Intramolecular Hydroacyloxylation of Unactivated Alkenes in Hexafluoroisopropanol
Qi, Chenxiao,Yang, Shengwen,Gandon, Vincent,Leb?uf, David
supporting information, p. 7405 - 7409 (2019/10/02)
We report an efficient intramolecular hydroacyloxylation of unactivated alkenes, offering a streamlined access to relevant γ-lactones, which features the utilization of either a calcium(II) salt or triflimide as a catalyst in hexafluoroisopropanol. This method could be applied to the synthesis of natural products and the late-stage functionalization of natural and bioactive molecules. Additionally, DFT computations were used to elucidate the twist of reactivity observed between the hydroamidation and hydroacyloxylation of unactivated alkenes regarding the formation of 5- and 6-membered rings.
Preparation method of gamma-caprolactone
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Paragraph 0036; 0037; 0038; 0045; 0046; 0047, (2017/08/28)
The invention provides a preparation method of gamma-caprolactone. The preparation method comprises the following steps of using at least one of 6-caprolactone, poly(epsilon-caprolactone) and 6-hydroxycaproic acid as a raw material and a Lewis acid as a catalyst, and carrying out rearrangement reaction under a condition that a reaction temperature is 50 to 250 DEG C, so that the gamma-caprolactone is obtained. According to the preparation method, through using the Lewis acid as the catalyst, the raw material is subjected to one-step conversion, so that the gamma-caprolactone can be obtained; the preparation method has the characteristics of simple process, easy purification, high yield, greenness, safety and the like, and is suitable for large-scale industrialized production.
Imidazo[1,2-a]pyridine-ylmethyl-derivatives and their use as flavoring agents
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, (2015/03/03)
The present invention primarily relates to imidazo[1,2-a]pyridine-ylmethyl-derivatives of Formula (I) wherein R1, R2, X, W e J are as defined in the description, to mixtures thereof and to the use thereof as flavoring agents. The compounds in accordance with the present invention are suitable for producing, imparting, or intensifying an umami flavor. The invention further relates to flavoring mixtures, compositions for oral consumption as well as ready-to-eat, ready-to-use and semifinished products, comprising an effective amount of the compound of Formula (I) and to specific methods for producing, imparting, modifying and/or intensifying specific flavor impressions.