
Journal of Medicinal Chemistry p. 206 - 212 (1990)
Update date:2022-09-26
Topics:
Yoshino
Nakazawa
Arakawa
Kaneko
Tsuchiya
Matsunaga
Araki
Ikeda
Yamatsu
Tachibana
In order to study the structure-activity relationships of dynorphin A-(1-8) amide [Dyn(1-8)-NH2], 20 analogues were synthesized by the solution method. Their biological activities were determined in the three bioassays [guinea pig ileum (GPI),
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