Synthesis and structure-activity relationships of dynorphin A-(1-8) amide analogues

DOI: 10.1021/jm00163a034

Source and publish data:

Journal of Medicinal Chemistry p. 206 - 212 (1990)

Update date:2022-09-26

Topics:

Authors:

Yoshino Yoshino

Nakazawa

Arakawa Arakawa

Kaneko Kaneko

Tsuchiya

Matsunaga

Araki Araki

Ikeda Ikeda

Yamatsu Yamatsu

Tachibana

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00163a034

In order to study the structure-activity relationships of dynorphin A-(1-8) amide [Dyn(1-8)-NH₂], 20 analogues were synthesized by the solution method. Their biological activities were determined in the three bioassays [guinea pig ileum (GPI),

Full text of DOI:10.1021/jm00163a034

Products guided by the article

Product name:Boc-Leu-Arg(Tos)-MeArg(Tos)-D-Leu-NHEt

Cas No:103613-75-8

R&D Labs maybe for 103613-75-8

Shanghai Bocimed Pharmaceutical Co., Ltd.

website:http://www.bocimed.com

Contact:+86-21-68861632

Address:Building 1, Lane 647, Songtao Road, Zhangjiang High-Tech Park, Shanghai
Chongqing maohuan Chemicals Co., Ltd

website:http://www.bschem.com

Contact:+86 13996103726

Address:Chongqing Nan'an District Tu Town
Reliable Pharma Technology (Shanghai) Co., Ltd.

Contact:0086-21-67676847-8008

Address:Lane 1500, No.68, Xinfei Road, Songjiang District, Shanghai, 201611, P.R.China.
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China
Kono Chem Co.,Ltd

website:http://www.konochem.com

Contact:86-29-86107037

Address:No.170 West Avenue,Xi’an 710082,China

Relevant to this article

Synthesis of oligo(spiroketal)s by polycondensation of silyl ethers derived from naturally occurring myo-inositol with 1,4-cyclohexanedione

Doi:10.1002/pola.29461
(2019)
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase

Doi:10.1016/j.bmc.2013.01.024
(2013)
Radical Anions of Chlorinated Benzaldehydes in Aqueuos Solution

Doi:10.1021/j100023a019
(1995)
JASPLAKINOLIDE, A CYCLODEPSIPEPTIDE FROM THE MARINE SPONGE, JASPIS SP.

Doi:10.1016/S0040-4039(00)84645-6
(1986)
RhCl₃/amine-catalyzed [2+2+2] cyclization of alkynes

Doi:10.1016/j.tet.2008.03.079
(2008)
Nucleophilic Additions to Triazolinedione Ylides, Extremely Reactive Carbonyl Equivalents: A New Class of Condensation Reactions

Doi:10.1021/jo00389a013
(1987)

Article Doi