A FACILE ONE-STEP SYNTHESIS OF 5'-PHOSPHATIDYLNUCLEOSIDES BY AN ENZYMATIC TWO-PHASE REACTION.

DOI: 10.1016/S0040-4039(00)95685-5

Source and publish data:

Tetrahedron Letters p. 199 - 202 (1987)

Update date:2022-08-02

Topics:

Authors:

Shuto, Satoshi

Ueda, Shigeru

Imamura, Shigeyuki

Fukukawa, Kiyofumi

Matsuda, Akira

Ueda, Tohru

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Article abstract of DOI:10.1016/S0040-4039(00)95685-5

Phospholipase D from Streptomyces effectively catalyzed the transfer reaction of the phosphatidyl residue from phosphatidylcholines to the 5'-hydroxyl group of nucleosides in a two-phase system.A variety of 5'-phosphatidylnucleosides were easily prepared in high yields by this reaction.

Full text of DOI:10.1016/S0040-4039(00)95685-5

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