Total Synthesis of Marine Mercaptohistidines: Ovothiols A, B, and C

DOI: 10.1021/jo00280a022

Source and publish data:

Journal of Organic Chemistry p. 4570 - 4575 (1989)

Update date:2022-09-26

Topics:

Authors:

Holler, Tod P.

Ruan, Fuqiang

Spaltenstein, Andreas

Hopkins, Paul B.

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Article abstract of DOI:10.1021/jo00280a022

Syntheses of ovothiols A and C in optically active form and ovothiols A and B in racemic form are reported.In all cases, synthesis of an S-protected mercaptoimidazole is followed by elaboration of an amino acid side chain.

Full text of DOI:10.1021/jo00280a022

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