Ergolines as selective 5-HT1 agonists

DOI: 10.1021/jm00403a007

Source and publish data:

Journal of Medicinal Chemistry p. 1512 - 1519 (1988)

Update date:2022-07-29

Topics:

Authors:

Ward Ward

Fuller Fuller

Merritt Merritt

Snoddy Snoddy

Paschal Paschal

Mason Mason

Horng Horng

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Article abstract of DOI:10.1021/jm00403a007

The synthesis and serotonin receptor subtype affinity of a series of ergolines are described. High selectivity for the 5-HT₁ subtype was found with a number of 8-substituted (3β,5β)-9,10-didehydro-6-methylergolines. The more potent and selectiv

Full text of DOI:10.1021/jm00403a007

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