Ergolines as selective 5-HT1 agonists

DOI: 10.1021/jm00403a007

Source and publish data:

Journal of Medicinal Chemistry p. 1512 - 1519 (1988)

Update date:2022-07-29

Topics:

Authors:

Ward Ward

Fuller Fuller

Merritt Merritt

Snoddy Snoddy

Paschal Paschal

Mason Mason

Horng Horng

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00403a007

The synthesis and serotonin receptor subtype affinity of a series of ergolines are described. High selectivity for the 5-HT₁ subtype was found with a number of 8-substituted (3β,5β)-9,10-didehydro-6-methylergolines. The more potent and selectiv

Full text of DOI:10.1021/jm00403a007

Products guided by the article

Product name:(3β,5β,8β)-9,10-didehydro-2,3-dihydro-6-methyl-8-[(methylthio)methyl]ergoline

Cas No:114249-78-4

R&D Labs maybe for 114249-78-4

Oren Hydrocarbons (Qingdao) Co., Ltd.

Contact:+86-532-68607667-801

Address:Room 3 # 302, No.9 Qingyun Road, Qingdao, China
Yicheng Goto Pharmaceuticals Co.,Ltd.

Contact:+86 710 3423122

Address:5th Floor,East Gate of Building #2,Servo-Industrial Park,1st Qilin Road,Xiangyang,Hubei,China
Nanjing Yuance Industry&Trade Co., Ltd.

website:http://www.njyuance.cn/

Contact:+86-25-85439097

Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
Anhui Sunsing Chemicals Co.,Ltd

website:http://www.sunsingchem.com

Contact:0086-566-2023179

Address:Jin An industry park, Chizhou economic technical development zone, Anhui
Shanghai Sungo Technology Chemical Co., Ltd

Contact:0086-21-51385579

Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA

Relevant to this article

Lewis acid induced rearrangement of 2,3-epoxy sulfides; regiospecific trapping of thiiranium ion intermediates with nitrogen heterocycles and amides. Use of imines as nucleophilic equivalents for the selective monoalkylation of primary amines

Doi:10.1016/0040-4020(96)00036-1
(1996)
Synthesis and biological properties of iron chelators based on a bis-2-(2-hydroxy-phenyl)-thiazole-4-carboxamide or -thiocarboxamide (BHPTC) scaffold

Doi:10.1016/j.bmc.2009.11.057
(2010)
Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys

Doi:10.1111/bph.14874
(2020)
Enantioselective cyanation of aldehydes catalyzed by bifunctional salen-aluminum complex

Doi:10.1016/j.catcom.2012.06.025
(2012)
Total synthesis of (±)-maistemonine, (±)-stemonamide, and (±)-isomaistemonine

Doi:10.1021/jo202042x
(2011)
Synthesis and molluscicidal activity of phosphorus-containing heterocyclic compounds derived from 5,6-bis (4-bromophenyl)-3-hydrazino-1,2,4-triazine

Doi:10.1080/10426500801967864
(2008)

Article Doi