
Journal of Organic Chemistry p. 9 - 10 (1989)
Update date:2022-08-02
Topics:
Schreiber, Stuart L.
Smith, David B.
The asymmetric synthesis of the cyclohexyl moiety of FK-506 is reported.The absolute stereogenicity of the target subunit was derived from the catalytic asymmetric synthesis of an epoxide by the method of Sharpless.
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