SYNTHESIS OF AN AROMATIC HYDROCARBON DIOL EPOXIDE-CYTOSINE ADDUCT, 5'-O-(9-PHENYLXANTHEN-9-YL)-N4--2'-DEOXYCYTIDINE, SUITABLE FOR INCORPORATION INTO SYNTHETIC OLIGODEOXYRIBONUCLEOTIDES

DOI: 10.1039/P19880002745

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2745 - 2750 (1988)

Update date:2022-09-26

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Authors:

Smith, Clive A.

Harper, Andrea E.

Coombs, Maurice M.

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Article abstract of DOI:10.1039/P19880002745

The first total synthesis of a model polyaromatic hydrocarbon diol epoxide-cytosine adduct is described, suitable for incorporation into oligodeoxyribonucleotide synthesis.An approach to control the relative stereochemistry of the diol epoxide-nucleoside

Full text of DOI:10.1039/P19880002745

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