A Stereoselective Synthesis of N--L-alanine Derivatives by Means of Reductive Amination

DOI: 10.1246/cl.1988.1691

Source and publish data:

Chemistry Letters p. 1691 - 1694 (1988)

Update date:2022-08-03

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Authors:

Iwasaki, Genji

Kimura, Rieko

Numao, Naganori

Kondo, Kiyoshi

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Article abstract of DOI:10.1246/cl.1988.1691

A stereoselective synthesis of N-<(S)-ethoxycarbonyl-3-phenylpropyl>-L-alanine, a portion of the molecule of angiotensin converting-enzyme(ACE) inhibitors, by reductive amination utilizing catecholborane and further applications of the reaction to the synthesis of ACE inhibitors are described.

Full text of DOI:10.1246/cl.1988.1691

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