A Stereoselective Synthesis of N--L-alanine Derivatives by Means of Reductive Amination

DOI: 10.1246/cl.1988.1691

Source and publish data:

Chemistry Letters p. 1691 - 1694 (1988)

Update date:2022-08-03

Topics:

Authors:

Iwasaki, Genji

Kimura, Rieko

Numao, Naganori

Kondo, Kiyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1988.1691

A stereoselective synthesis of N-<(S)-ethoxycarbonyl-3-phenylpropyl>-L-alanine, a portion of the molecule of angiotensin converting-enzyme(ACE) inhibitors, by reductive amination utilizing catecholborane and further applications of the reaction to the synthesis of ACE inhibitors are described.

Full text of DOI:10.1246/cl.1988.1691

Products guided by the article

Product name:(S)-1-[(S)-6-tert-Butoxycarbonylamino-2-((R)-1-ethoxycarbonyl-3-phenyl-propylamino)-hexanoyl]-pyrrolidine-2-carboxylic acid tert-butyl ester

Cas No:120199-98-6

R&D Labs maybe for 120199-98-6

Changsha Yonta Industry Co., Ltd.

Contact:+ 86-731-8535 2228

Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.

Contact:15967177856

Address:Genglou Industrial Development Area
EGBERT CORPORATION

Contact:+86 18616952870

Address:Area
JiYi Chemical (Beijing) Co., Ltd.

Contact:+86-10-89385733

Address:Shilou Town of Fangshan District， Beijing
Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing

Relevant to this article

Syntheses and structures of the lithiumtitanates(III)/(IV) (py) ₂Li[(py)₂Ti(OPh)₄] and (py)₂Li[(py) Ti(OPh)₅]

Doi:10.1002/zaac.200800382
(2009)
Counterion effects on the mesomorphic properties of chiral imidazolium and pyridinium ionic liquids

Doi:10.1002/ejoc.200900730
(2009)
Synthesis of phthalic acid derivatives: Via Pd-catalyzed alkoxycarbonylation of aromatic C-H bonds with alkyl chloroformates

Doi:10.1039/c8cc06663a
(2018)
SYNTHESIS OF MACROHETEROCYCLES - ANALOGS OF DIBENZO-CROWN COMPOUNDS. 2. 18-MEMBERED DIOXADIAZA-CROWN COMPOUNDS

Doi:10.1007/BF00479353
(1988)
FACILE SYNTHESIS OF α-PHOSPHORYLATED α-AMINO ACIDS

Doi:10.1016/S0040-4039(00)80523-7
(1988)
REACTION OF 5-HYDROXY-N-ARYL-1,4-NAPHTHOQUINON-4-IMINES WITH PRIMARY ALIPHATIC AMINES

Doi:10.1007/BF00962769
(1988)

Article Doi