Cycloaddition reactions of cephalosporin compounds. XI [1]. 1,3-dipolar cycloaddition reaction of an exo-2-methylenecephem with diphenyldiazomethane

DOI: 10.1002/jhet.5570260238

Source and publish data:

Journal of Heterocyclic Chemistry p. 461 - 464 (1989)

Update date:2022-08-03

Topics:

Authors:

Pitlik Pitlik

Jaszberenyi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570260238

In the 1,3-dipolar cycloaddition reaction of the exo-2-methylenecephem 6 with diphenyldiazomethane the initially formed pyrazolines decompose and spirocyclopropylcephalosporin formation takes place. The structure elucidation with ¹H, ¹³C, ASIS and NOE nmr methods is also described.

Full text of DOI:10.1002/jhet.5570260238

Products guided by the article

Product name:Methyl (2R)-7-Chloroacetamido-2-(2',2'-diphenylspirocyclopropyl)-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate 1S-(β)-Oxide

Cas No:123457-02-3

R&D Labs maybe for 123457-02-3

shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Shanghai Hohance Chemical Co., ltd

Contact:13914753421

Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Suzhou Kangrun Pharmaceutical, Inc

Contact:86-512-63912376，63913329

Address:Building 2, No. 2358 ,Chang'an Rd, Wujiang Economic Development Zone Pioneering park, china
Weifang Arylchem Chemical Co., LTD

Contact:86-536-5217866

Address:Development Zone, Shouguang, Shandong Province

Relevant to this article

Reaction of salicylalkylenediimines with 2-chloro-4,5-diphenyl-1,3,2- dioxaphospholene

Doi:10.1134/S1070363210020313
(2010)
A Sulfur-sulfur cross-linked polymer synthesized from a polymerizable dithiocarbamate as a source of dormant radicals

Doi:10.1002/anie.200906676
(2010)
Acetic acid aldol reactions in the presence of trimethylsilyl trifluoromethanesulfonate

Doi:10.1021/jo100828c
(2010)
Synthesis, structural characterization and catalytic activity of a palladium(II) complex bearing a new ditopic thiophene-N-heterocyclic carbene ligand

Doi:10.1016/j.ica.2009.02.035
(2010)
Dimethyl isosorbideviaorganocatalystN-methyl pyrrolidine: scaling up, purification and concurrent reaction pathways

Doi:10.1039/d1cy00465d
(2021)
5- N,4- O -carbonyl-7,8,9-tri- O -chloroacetyl-protected sialyl donor for the stereoselective synthesis of α-(2→9)-tetrasialic acid

Doi:10.1021/jo100824s
(2010)

Article Doi