An Enantioselective Synthesis of (+)-Picrasin B, (+)-Δ2-Picrasin B, and (+)-Quassin from the R-(-) Enantiomer of the Wieland-Miescher Ketone

Article abstract of DOI:10.1021/jo00289a023

An enantioselective total synthesis of (+)-picrasin B (1), (+)-Δ²-picrasin B (11), and (+)-quassin (12) from the R-(-) enantiomer of the Wieland-Miescher ketone (3) employed an A-AB-ABC-ABCD sequence to assemble the tetracyclic skeleton.The cru