CONVERGENT APPROACH TO INTERMEDIATES USED FOR THE SYNTHESIS OF THE ENEDIYNE STRUCTURE OF THE ESPERAMICINS AND CALICHEAMICINS

DOI: 10.1016/S0040-4039(00)99423-1

Source and publish data:

Tetrahedron Letters p. 3499 - 3500 (1989)

Update date:2022-07-29

Topics:

Authors:

Kadow, J. F.

Saulnier, M. G.

Tun, M. M.

Langley, D. R.

Vyas, D. M.

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Article abstract of DOI:10.1016/S0040-4039(00)99423-1

The diynene lithium acetylide 5 adds to 2-siloxy-2-cyclohexenone 6 followed by silyl migration to produce ketone adduct 7, an intermediate towards a simple Esperamicin core

Full text of DOI:10.1016/S0040-4039(00)99423-1

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