CONVERGENT APPROACH TO INTERMEDIATES USED FOR THE SYNTHESIS OF THE ENEDIYNE STRUCTURE OF THE ESPERAMICINS AND CALICHEAMICINS

DOI: 10.1016/S0040-4039(00)99423-1

Source and publish data:

Tetrahedron Letters p. 3499 - 3500 (1989)

Update date:2022-07-29

Topics:

Authors:

Kadow, J. F.

Saulnier, M. G.

Tun, M. M.

Langley, D. R.

Vyas, D. M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)99423-1

The diynene lithium acetylide 5 adds to 2-siloxy-2-cyclohexenone 6 followed by silyl migration to produce ketone adduct 7, an intermediate towards a simple Esperamicin core

Full text of DOI:10.1016/S0040-4039(00)99423-1

Products guided by the article

Product name:2-(tert-Butyl-dimethyl-silanyloxy)-2-[(Z)-7-(tert-butyl-dimethyl-silanyloxy)-hept-3-ene-1,5-diynyl]-cyclohexanone

Cas No:124571-85-3

R&D Labs maybe for 124571-85-3

shanghai tuomiao chemicial co.,ltd.

website:https://www.tuomiaochem.com/

Contact:021 - 59853336

Address:shanghai
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China
Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Shanghai Hope Chem Co., Ltd

website:http://www.hope-chem.com

Contact:86-21-58090396-805

Address:Floor 4, Building 5, No.588 Tianxiong Road, Zhoupu International Medical Zone, ShangHai, China
Cangzhou Senary Chemical Science-tech Co., Ltd

Contact:+86-317-3563899, 3563699

Address:168 Jinde Road, Cangzhou, Hebei, China

Relevant to this article

Base-Catalyzed Selective Synthesis of 2-Azabicyclo[3.2.0]hept-2-enes and Sulfonyl Vinyl-Substituted Pyrroles from 3-Aza-1,5-enynes

Doi:10.1021/acs.orglett.5b01474
(2015)
Asymmetric cooperative catalysis in the conjugate addition of pyrazolones to nitroolefins and subsequent dearomative chlorination

Doi:10.1007/s11426-013-5017-3
(2014)
Alkylidene Carbenes as Intermediates in the Synthesis of Highly Functionalized Branched-chain Sugar and Nucleosides

Doi:10.1016/S0040-4020(01)85250-9
(1994)
Enantioselective gold(I)-catalyzed vinylogous [3 + 2] cycloaddition between vinyldiazoacetates and enol ethers

Doi:10.1021/ja407179c
(2013)
Catalyst-and metal-free rapid functionalizations of alkynes using TsNBr₂

Doi:10.1055/s-0033-1339194
(2013)
Synthesis, physicochemical studies, molecular dynamics simulations, and metal-ion-dependent antiproliferative and antiangiogenic properties of cone ICL670-substituted calix[4]arenes

Doi:10.1002/cplu.201200141
(2012)

Article Doi