Stereocontrolled Synthesis of Andrimid and a Structural Requirement for the Activity

DOI: 10.1039/c39890000299

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 299 - 301 (1989)

Update date:2022-08-04

Topics:

Authors:

McWhorter, William

Fredenhagen, Andreas

Nakanishi, Koji

Komura, Hajime

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39890000299

Total synthesis of an antibiotic Andrimid was accomplished stereospecifically: it was shown that the chiralities at C-3 and C-4 should be R and S, respectively, and the presence of the (4S)-methyl group is important for the activity.

Full text of DOI:10.1039/c39890000299

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(2S,3R,5S)-5-tert-Butoxycarbonylamino-3-carbamoyl-2,6-dimethyl-4-oxo-heptanoic acid benzyl ester

Cas No:124817-98-7

R&D Labs maybe for 124817-98-7

jiangsu haian chemical co.,ltd.

Contact:86-513-15851283853

Address:No.99,Changjiang West Road,Haian County,Jiangsu Province,China
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
SHANGHAI T&W PHARMACEUTICAL CO., LTD.

website:http://www.trustwe.com

Contact:+86-21-61551611

Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
MedicalChem(Yancheng)Manuf.Co.,Ltd.

Contact:+86-515-84383366

Address:Touzeng BinHai, YanCheng City, JiangSu Province, China

Relevant to this article

New Irone-Related Constituents from the Essential Oil of Iris Germanica L.

Doi:10.1002/hlca.19890720629
(1989)
Synthesis and biological activity of D₃-trishomocubyl-4-amines

Doi:10.1021/jm00106a053
(1991)
Synthesis and anticoccidial activities of eight novel ethyl 7-alkyl-6-(2-aryloxyethoxy)-4-hydroxyquinoline-3-carboxylates

Doi:10.3184/030823410X12651249924554
(2010)
Synthesis, and evaluation of in vitro and in vivo anticancer activity of 14-substituted oridonin analogs: A novel and potent cell cycle arrest and apoptosis inducer through the p53-MDM2 pathway

Doi:10.1016/j.ejmech.2019.04.005
(2019)
THE STUDY OF INTRAMOLECULAR FREE RADICAL CYCLIZATION OF α-SULFENYL RADICAL

Doi:10.1016/S0040-4039(01)93728-1
(1989)
ATTEMPTED SIMMONS-SMITH REACTION ON α-OXOKETENE DITHIOACETALS: A NEW GENERAL ROUTE TO 3,4-SUBSTITUTED AND ANNELATED THIOPHENES

Doi:10.1016/S0040-4039(00)99411-5
(1989)

Article Doi