Tetrahedron Letters p. 5263 - 5266 (1994)
Update date:2022-08-02
Topics:
Ishihara, Takashi
Yamaguchi, Koichi
Kuroboshi, Manabu
Utimoto, Kiitiro
The syn and anti isomers of 2-fluoro-2-(trifluoromethyl)-3-hydroxy ketones are reduced in a highly 1,2-syn diastereoselective manner with lithium aluminum hydride or diisobutylaluminum hydride in tetrahydrofuran at -78 degC, affording 1,2-syn-2,3-syn- and
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