A convenient, large-scale preparation of 2,4-dichlorophenyl-4- bromomethyl-phenoxyacetate suitable for resin anchorage of the first Fmoc amino acid

Article abstract of DOI:10.1080/00397919408011495

2,4-dichlorophenyl-4-bromomethyl-phenoxyacetate 3 was prepared by NBS treatment of 2,4-dichlorophenyl-4-methylphenoxacetate 2. This ester is a key intermediate in the preparation of 2,4-dichlorophenyl-N(α)-Fmoc-aminoacyl- 4-oxymethylphenoxy-acetates suitable for anchorage of the first amino acid on amine-functionalized polymers.

Full text of DOI:10.1080/00397919408011495

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Convenient, Large-
Scale Preparation of
2,4-Dichlorophenyl-4-
bromomethyl-phenoxyacetate
Suitable for Resin Anchorage of
the First Fmoc Amino Acid
Loic René a & Bernard Badet a
a Institut de Chimie des Substances Naturelles,
C.N.R.S. , 91198, Gif-sur-Yvette, Cedex, France
Published online: 04 Jan 2007.
To cite this article: Loic René & Bernard Badet (1994) A Convenient, Large-Scale
Preparation of 2,4-Dichlorophenyl-4-bromomethyl-phenoxyacetate Suitable for Resin
Anchorage of the First Fmoc Amino Acid, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 24:4, 463-465, DOI:
10.1080/00397919408011495
To link to this article: http://dx.doi.org/10.1080/00397919408011495
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