Asymmetric synthesis of malic acid-type synthons VIA chiral norephedrine-derived oxazolidines

DOI: 10.1016/S0040-4020(01)89766-0

Source and publish data:

Tetrahedron p. 1987 - 1998 (1990)

Update date:2022-08-05

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Authors:

Bernardi, Anna

Cardani, Silvia

Scolastico, Carlo

Villa, Roberto

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Article abstract of DOI:10.1016/S0040-4020(01)89766-0

Polyoxygenated C₄ synthons 5-7 are synthesized in enantiomerically pure form starting from ephedrine derived oxazolidines 2,4 and 13. The 1,4-benzylate addition to 2 and 4, the key step in the synthesis of 5 and 6, proceeds cleanly with almost

Full text of DOI:10.1016/S0040-4020(01)89766-0

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