Synthesis of antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides

DOI: 10.1021/jm00171a025

Source and publish data:

Journal of Medicinal Chemistry p. 2494 - 2501 (1990)

Update date:2022-08-05

Topics:

Authors:

Bamford Bamford

Coe Coe

Walker Walker

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a025

A series of 3'-branched-chain sugar nucleosides, in particular 3'-deoxy-3'-C-hydroxymethyl nucleosides, have been synthesized and evaluated as antiviral agents. Reaction of 1-(2,3-epoxy-5-O-trityl-β-D-lyxo-pentafuranosyl) derivatives 12 and 13, of uracil

Full text of DOI:10.1021/jm00171a025

Products guided by the article

Product name:1-[(2R,3S,4S,5S)-3-Hydroxy-4-(5-methyl-[1,3,5]dithiazinan-2-yl)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

Cas No:130351-53-0

R&D Labs maybe for 130351-53-0

Exploiter Molybdenum Co.,Ltd

Contact:86-379-63338609

Address:Jiudian Village,Deting Town,Song County,Luoyang
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
Liaoyang Xinyou Chemical Products Co.,Ltd.

Contact:+86-419-5165433 13604191870

Address:Huishang Road6-1, Hongwei District, Liaoyang, Liaoning, China
waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
Shanghai Run-Biotech Co., Ltd.

website:http://www.run-biotech.com

Contact:+86-21-31576854/57171705 / 57171706

Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China

Relevant to this article

Synthetic Studies on (-)-Tetrodotoxin (3) Nitrogenation through Overman Rearrangement and Guanidine Ring Formation

Doi:10.1016/S0040-4039(00)89056-5
(1990)
PHOTOOXYGENIERUNG VON 1-ARYL-2,2-DIMETHYLBICYCLO<1.1.0>BUTANEN

Doi:10.1016/S0040-4039(00)97682-2
(1990)
A formal total synthesis of (-)-isoavenaciolide from L-quebrachitol

Doi:10.1039/c39900000994
(1990)
A Convenient Synthesis of 8-Substituted Indolizines as Precursors to 5-Substituted Cycl{3.2.2}azine Derivatives

Doi:10.1002/jhet.5570340511
(1997)
Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products

Doi:10.1021/jacs.7b01624
(2017)
Palladium-catalyzed decarboxylative arylation of potassium cyanoacetate: Synthesis of α-diaryl nitriles from aryl halides

Doi:10.1021/ol2009522
(2011)

Article Doi