Synthesis of antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides

DOI: 10.1021/jm00171a025

Source and publish data:

Journal of Medicinal Chemistry p. 2494 - 2501 (1990)

Update date:2022-08-05

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Authors:

Bamford Bamford

Coe Coe

Walker Walker

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Article abstract of DOI:10.1021/jm00171a025

A series of 3'-branched-chain sugar nucleosides, in particular 3'-deoxy-3'-C-hydroxymethyl nucleosides, have been synthesized and evaluated as antiviral agents. Reaction of 1-(2,3-epoxy-5-O-trityl-β-D-lyxo-pentafuranosyl) derivatives 12 and 13, of uracil

Full text of DOI:10.1021/jm00171a025

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