Tetrahedron p. 12277 - 12284 (1995)
Update date:2022-08-04
Topics:
Veronese, Augusto C.
Callegari, Rosella
Morelli, Carlo F.
Ortho-aminobenzonitriles 1 react with β-ketoesters and alkyl malonates, in the presence of stoichiometric amounts of tin (IV) chloride, to give 4-aminoquinolines 2 and 4-amino-2-quinolones 3 respectively. Similarly β-enaminonitriles 7 afford 4-aminopyridi
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