Synthesis p. 539 - 542 (1991)
Update date:2022-07-29
Topics:
Zhuangyu
Yi
Honwen
Tsi-yu
Several arylacetaldehydes 5 were synthesized in moderate yields via Heck reaction of acrylamide (1) with substituted iodobenzenes 2 in the presence of the polymeric catalyst (P)-phenyl-(1,10-phenanthroline)-palladium(0) [(P)-ph-phen·Pd(0)] followed by Hofmann reaction and subsequent hydrolysis.
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