Synthetic applications of 2-aryl-4-piperidones. VIII. Synthesis of methyl indolo[2,3-a]quinolizidin-2-acetate

DOI: 10.1016/S0040-4039(00)91905-1

Source and publish data:

Tetrahedron Letters p. 1233 - 1236 (1992)

Update date:2022-08-04

Topics:

Authors:

Rubiralta, Mario

Diez, Anna

Vila, Cristina

Bettiol, Jean-Luc

Troin, Yves

Sinibaldi, Marie-Eve

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Article abstract of DOI:10.1016/S0040-4039(00)91905-1

The synthesis of methyl indolo[2,3-a]quinolizidin-2-acetate (21) from 1-hydroxyethyl-2-[1-(phenylsulfonyl)-3-indolyl]piperidine-4-acetate (16) by an intramolecular cyclization induced by K^tBuO is described.

Full text of DOI:10.1016/S0040-4039(00)91905-1

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