Tetrahedron Letters p. 4213 - 4216 (1992)
Update date:2022-08-02
Topics:
Deshpande, V. H.
Gokhale, Neelam J.
The synthesis of combretastatin D-2 methyl ether (2) by macrolactonization of hydroxy acid 11 under modified Mitsunobu conditions is described.In accord with the literature, attempts to cyclize 11 via various conventional macrolactonization methods failed.
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