Enzymatic Synthesis of Optically Active 2-Carbamoyloxymethyl-1,4-dihydropyridines, (R)-(+)- and (S)-(-)-NB 818

DOI: 10.1016/S0957-4166(00)82100-X

Source and publish data:

Tetrahedron Asymmetry p. 1153 - 1156 (1992)

Update date:2022-07-30

Topics:

Authors:

Ebiike, Hirosato

Maruyama, Kaori

Achiwa, Kazuo

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Article abstract of DOI:10.1016/S0957-4166(00)82100-X

Racemic dihydropyridines were resolved by enzyme-catalyzed hydrolysis in an organic solvent saturated with water.The chiral derivatives obtained were converted to (S)- and (R)-NB 818.

Full text of DOI:10.1016/S0957-4166(00)82100-X

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