Tetrahedron Letters p. 63 - 66 (1993)
Update date:2022-08-02
Topics:
Smith, Amos B.
Holcomb, Ryan C.
Guzman, Mark C.
Keenan, Terence P.
Sprengeler, Paul A.
Hirschmann, Ralph
A new two-step method employs the intramolecular cyclization of metalated imino esters for the construction of scalemic 3,5,5-trisubstituted pyrrolin-4-ones (4).The imino esters in turn derive from α-disubstituted amino acids, the latter readily available
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Doi:10.1016/S0040-4020(01)81870-6
(1993)Doi:10.1002/chem.201302665
(2013)Doi:10.1016/0022-328X(93)83081-6
(1993)Doi:10.1021/jm400898x
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